Immunoglobulin superfamily cell adhesion molecules: zippers and signals Export

@article{citeulike:2294593, abstract = {The latest structural studies of immunoglobulin superfamily cell adhesion molecules are driving a shift in perspective; increasingly the view is not focused solely on the individual molecule but rather is on the molecular assembly. Two common themes are emerging, revealing mechanisms for ectodomain-dependent regulation of cell surface receptors' signalling abilities. The first is the propensity of many such molecules to arrange in zipper-type or array-type assemblies driven by a network of highly specific cis and trans interactions. The second is the use of the extracellular dimensions of a molecule or adhesion complex as properties which, in combination with characteristic intercellular spacings, can determine the co-localisation or exclusion of particular protein populations at cell interfaces and junctions.}, author = {Aricescu, Radu A. and Jones, Yvonne E.}, booktitle = {Cell to cell contact and extracellular matrix}, citeulike-article-id = {2294593}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.ceb.2007.09.010}, citeulike-linkout-1 = {http://www.sciencedirect.com/science/article/B6VRW-4PYRK9V-3/2/b55a5653c2153e247267a0172d4b5358}, doi = {10.1016/j.ceb.2007.09.010}, journal = {Current Opinion in Cell Biology}, keywords = {cell-adhesion, ig-like}, month = {October}, number = {5}, pages = {543--550}, posted-at = {2008-01-27 08:53:59}, priority = {0}, title = {Immunoglobulin superfamily cell adhesion molecules: zippers and signals}, url = {http://dx.doi.org/10.1016/j.ceb.2007.09.010}, volume = {19}, year = {2007} }

TY - JOUR ID - citeulike:2294593 L3 - citeulike-article-id:2294593 N2 - The latest structural studies of immunoglobulin superfamily cell adhesion molecules are driving a shift in perspective; increasingly the view is not focused solely on the individual molecule but rather is on the molecular assembly. Two common themes are emerging, revealing mechanisms for ectodomain-dependent regulation of cell surface receptors' signalling abilities. The first is the propensity of many such molecules to arrange in zipper-type or array-type assemblies driven by a network of highly specific cis and trans interactions. The second is the use of the extracellular dimensions of a molecule or adhesion complex as properties which, in combination with characteristic intercellular spacings, can determine the co-localisation or exclusion of particular protein populations at cell interfaces and junctions. IS - 5 JF - Current Opinion in Cell Biology EP - 550 TI - Immunoglobulin superfamily cell adhesion molecules: zippers and signals VL - 19 T2 - Cell to cell contact and extracellular matrix SP - 543 KW - cell-adhesion KW - ig-like AU - Aricescu, Radu AU - Jones, Yvonne PY - 2007/10// UR - http://dx.doi.org/10.1016/j.ceb.2007.09.010 ER -