Systems biology of bacterial chemotaxis. Export

@article{2006Baker, abstract = {Motile bacteria regulate chemotaxis through a highly conserved chemosensory signal-transduction system. System-wide analyses and mathematical modeling are facilitated by extensive experimental observations regarding bacterial chemotaxis proteins, including biochemical parameters, protein structures and protein-protein interaction maps. Thousands of signaling and regulatory chemotaxis proteins within a bacteria cell form a highly interconnected network through distinct protein-protein interactions. A bacterial cell is able to respond to multiple stimuli through a collection of chemoreceptors with different sensory modalities, which interact to affect the cooperativity and sensitivity of the chemotaxis response. The robustness or insensitivity of the chemotaxis system to perturbations in biochemical parameters is a product of the system's hierarchical network architecture.}, address = {Princeton University, Department of Molecular Biology, Lewis Thomas Laboratory, Princeton, NJ 08544, USA.}, author = {Baker, M. D. and Wolanin, P. M. and Stock, J. B.}, citeulike-article-id = {1217826}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.mib.2006.02.007}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/16529985}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=16529985}, citeulike-linkout-3 = {http://www.sciencedirect.com/science/article/B6VS2-4JF9973-3/2/f39c2216881036b5e44d2d689133f69a}, doi = {10.1016/j.mib.2006.02.007}, issn = {1369-5274}, journal = {Curr Opin Microbiol}, keywords = {bacterial, biology, ch1, chemotaxis, refs\_ox, systems}, month = {April}, number = {2}, pages = {187--192}, posted-at = {2007-04-09 12:40:01}, priority = {2}, title = {Systems biology of bacterial chemotaxis.}, url = {http://dx.doi.org/10.1016/j.mib.2006.02.007}, volume = {9}, year = {2006} }

TY - JOUR ID - 2006Baker L3 - citeulike-article-id:1217826 N2 - Motile bacteria regulate chemotaxis through a highly conserved chemosensory signal-transduction system. System-wide analyses and mathematical modeling are facilitated by extensive experimental observations regarding bacterial chemotaxis proteins, including biochemical parameters, protein structures and protein-protein interaction maps. Thousands of signaling and regulatory chemotaxis proteins within a bacteria cell form a highly interconnected network through distinct protein-protein interactions. A bacterial cell is able to respond to multiple stimuli through a collection of chemoreceptors with different sensory modalities, which interact to affect the cooperativity and sensitivity of the chemotaxis response. The robustness or insensitivity of the chemotaxis system to perturbations in biochemical parameters is a product of the system's hierarchical network architecture. IS - 2 JF - Curr Opin Microbiol SN - 1369-5274 AD - Princeton University, Department of Molecular Biology, Lewis Thomas Laboratory, Princeton, NJ 08544, USA. EP - 192 TI - Systems biology of bacterial chemotaxis. VL - 9 SP - 187 KW - bacterial KW - biology KW - ch1 KW - chemotaxis KW - refs_ox KW - systems AU - Baker, MD AU - Wolanin, PM AU - Stock, JB PY - 2006/04// UR - http://dx.doi.org/10.1016/j.mib.2006.02.007 ER -