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Processing the H3K36me3 signature Export

Nat Genet, Vol. 41, No. 3. (01 March 2009), pp. 270-271.

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chromatin exon h3k36 intron

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The global patterning of histone lysine methylation has been scrutinized over the years in an effort to uncover unique features indicative of chromatin function. A study in Caenorhabditis elegans now shows that nucleosomes covering exons and introns on active genes are differentially marked by H3K36 trimethylation, suggesting a new mode of communication between chromatin and pre-mRNA processing.


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