The transcriptional regulatory code of eukaryotic cells - insights from genome-wide analysis of chromatin organization and transcription factor binding Export

@article{citeulike:663253, abstract = {Control of eukaryotic gene expression involves combinatorial interactions between transcription factors and regulatory sequences in the genome. In addition, chromatin structure and modification states play key roles in determining the competence of transcription. The term 'transcriptional regulatory code' has been used to describe the interplay of these events in the complex control of transcription. With the maturation of methods for detecting in vivo protein-DNA interactions on a genome-wide scale, detailed maps of chromatin features and transcription factor localization over entire genomes of eukaryotic cells are enriching our understanding of the properties and nature of this transcriptional regulatory code. The rapidly growing number of maps has revealed the dynamic nature of nucleosome composition and chromatin remodeling at regulatory regions and highlighted some unexpected properties of transcriptional regulatory networks in eukaryotic cells.}, author = {Barrera, Leah O. and Ren, Bing}, booktitle = {Nucleus and gene expression}, citeulike-article-id = {663253}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.ceb.2006.04.002}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/16647254}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=16647254}, citeulike-linkout-3 = {http://www.sciencedirect.com/science/article/B6VRW-4JVSVDC-1/2/616616e7fbca5e7196a2ab8a2fce1391}, doi = {10.1016/j.ceb.2006.04.002}, journal = {Current Opinion in Cell Biology}, keywords = {molecular\_biology}, month = {June}, number = {3}, pages = {291--298}, posted-at = {2006-05-21 18:30:04}, priority = {2}, title = {The transcriptional regulatory code of eukaryotic cells - insights from genome-wide analysis of chromatin organization and transcription factor binding}, url = {http://dx.doi.org/10.1016/j.ceb.2006.04.002}, volume = {18}, year = {2006} }

TY - JOUR ID - citeulike:663253 L3 - citeulike-article-id:663253 N2 - Control of eukaryotic gene expression involves combinatorial interactions between transcription factors and regulatory sequences in the genome. In addition, chromatin structure and modification states play key roles in determining the competence of transcription. The term 'transcriptional regulatory code' has been used to describe the interplay of these events in the complex control of transcription. With the maturation of methods for detecting in vivo protein-DNA interactions on a genome-wide scale, detailed maps of chromatin features and transcription factor localization over entire genomes of eukaryotic cells are enriching our understanding of the properties and nature of this transcriptional regulatory code. The rapidly growing number of maps has revealed the dynamic nature of nucleosome composition and chromatin remodeling at regulatory regions and highlighted some unexpected properties of transcriptional regulatory networks in eukaryotic cells. IS - 3 JF - Current Opinion in Cell Biology EP - 298 TI - The transcriptional regulatory code of eukaryotic cells - insights from genome-wide analysis of chromatin organization and transcription factor binding VL - 18 T2 - Nucleus and gene expression SP - 291 KW - molecular_biology AU - Barrera, Leah AU - Ren, Bing PY - 2006/06// UR - http://dx.doi.org/10.1016/j.ceb.2006.04.002 ER -