Perspectives in the control of infectious diseases by transgenic mosquitoes in the post-genomic era: a review.

@article{citeulike:1442555, abstract = {Arthropod-borne diseases caused by a variety of microorganisms such as dengue virus and malaria parasites afflict billions of people worldwide imposing major economic and social burdens. Despite many efforts, vaccines against diseases transmitted by mosquitoes, with the exception of yellow fever, are not available. Control of such infectious pathogens is mainly performed by vector management and treatment of affected individuals with drugs. However, the numbers of insecticide-resistant insects and drug-resistant parasites are increasing. Therefore, inspired in recent years by a lot of new data produced by genomics and post-genomics research, several scientific groups have been working on different strategies to control infectious arthropod-borne diseases. This review focuses on recent advances and perspectives towards construction of transgenic mosquitoes refractory to malaria parasites and dengue virus transmission.}, address = {Faculdade de Medicina de Mar\'{i}lia, Mar\'{i}lia, SP, Brasil.}, author = {Sperança, M. A. and Capurro, M. L. }, citeulike-article-id = {1442555}, issn = {0074-0276}, journal = {Mem Inst Oswaldo Cruz}, keywords = {review, transgenic\_mosquitoes}, month = {July}, number = {4}, pages = {425--433}, posted-at = {2007-07-08 11:20:06}, priority = {2}, title = {Perspectives in the control of infectious diseases by transgenic mosquitoes in the post-genomic era: a review.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/17612761}, volume = {102}, year = {2007} }

TY - JOUR ID - citeulike:1442555 L3 - citeulike-article-id:1442555 TI - Perspectives in the control of infectious diseases by transgenic mosquitoes in the post-genomic era: a review. JF - Mem Inst Oswaldo Cruz VL - 102 IS - 4 SP - 425 EP - 433 AD - Faculdade de Medicina de Marília, Marília, SP, Brasil. SN - 0074-0276 N2 - Arthropod-borne diseases caused by a variety of microorganisms such as dengue virus and malaria parasites afflict billions of people worldwide imposing major economic and social burdens. Despite many efforts, vaccines against diseases transmitted by mosquitoes, with the exception of yellow fever, are not available. Control of such infectious pathogens is mainly performed by vector management and treatment of affected individuals with drugs. However, the numbers of insecticide-resistant insects and drug-resistant parasites are increasing. Therefore, inspired in recent years by a lot of new data produced by genomics and post-genomics research, several scientific groups have been working on different strategies to control infectious arthropod-borne diseases. This review focuses on recent advances and perspectives towards construction of transgenic mosquitoes refractory to malaria parasites and dengue virus transmission. KW - review KW - transgenic_mosquitoes AU - Sperança, MA AU - Capurro, ML PY - 2007/07// UR - http://view.ncbi.nlm.nih.gov/pubmed/17612761 ER -