In search of antisense. Export

@article{citeulike:3893573, abstract = {In recent years, natural antisense transcripts (NATs) have been implicated in many aspects of eukaryotic gene expression including genomic imprinting, RNA interference, translational regulation, alternative splicing, X-inactivation and RNA editing. Moreover, there is growing evidence to suggest that antisense transcription might have a key role in a range of human diseases. Consequently, there have been several recent attempts to identify novel NATs. To date, approximately 2500 mammalian NATs have been found, indicating that antisense transcription might be a common mechanism of regulating gene expression in human cells. There are increasingly diverse ways in which antisense transcription can regulate gene expression and evidence for the involvement of NATs in human disease is emerging. A range of bioinformatic resources could be used to assist future antisense research.}, author = {Lavorgna, Giovanni and Dahary, Dvir and Lehner, Ben and Sorek, Rotem and Sanderson, Christopher M. and Casari, Giorgio}, citeulike-article-id = {3893573}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.tibs.2003.12.002}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/15102435}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=15102435}, doi = {10.1016/j.tibs.2003.12.002}, issn = {0968-0004}, journal = {Trends in biochemical sciences}, keywords = {antisense}, month = {February}, number = {2}, pages = {88--94}, posted-at = {2009-01-17 09:21:13}, priority = {0}, title = {In search of antisense.}, url = {http://dx.doi.org/10.1016/j.tibs.2003.12.002}, volume = {29}, year = {2004} }

TY - JOUR ID - citeulike:3893573 L3 - citeulike-article-id:3893573 N2 - In recent years, natural antisense transcripts (NATs) have been implicated in many aspects of eukaryotic gene expression including genomic imprinting, RNA interference, translational regulation, alternative splicing, X-inactivation and RNA editing. Moreover, there is growing evidence to suggest that antisense transcription might have a key role in a range of human diseases. Consequently, there have been several recent attempts to identify novel NATs. To date, approximately 2500 mammalian NATs have been found, indicating that antisense transcription might be a common mechanism of regulating gene expression in human cells. There are increasingly diverse ways in which antisense transcription can regulate gene expression and evidence for the involvement of NATs in human disease is emerging. A range of bioinformatic resources could be used to assist future antisense research. IS - 2 JF - Trends in biochemical sciences SN - 0968-0004 EP - 94 TI - In search of antisense. VL - 29 SP - 88 KW - antisense AU - Lavorgna, Giovanni AU - Dahary, Dvir AU - Lehner, Ben AU - Sorek, Rotem AU - Sanderson, Christopher AU - Casari, Giorgio PY - 2004/02// UR - http://dx.doi.org/10.1016/j.tibs.2003.12.002 ER -