A model for the interaction of two chemicals

@article{citeulike:1495980, abstract = {We describe a method for studying the interaction of two anesthetic agents, Morphine and Midazolam, acting simultaneously in the same individual. Representing the levels of the two chemicals by diffusion processes, we assume their interaction is governed by a linear combination of the separate components. Pharmacological data is used to estimate the model parameters and, in particular, to determine the coefficient in the linear combination. This leads to the conclusion that the two chemicals have a counteractive effect.}, author = {Sen, Pali and Bell, Denis }, citeulike-article-id = {1495980}, doi = {http://dx.doi.org/10.1016/j.jtbi.2005.06.013}, journal = {Journal of Theoretical Biology}, keywords = {biorefs, reaction-diffusion}, month = {February}, number = {3}, pages = {652--656}, posted-at = {2007-07-26 14:51:17}, priority = {2}, title = {A model for the interaction of two chemicals}, url = {http://dx.doi.org/10.1016/j.jtbi.2005.06.013}, volume = {238}, year = {2006} }

TY - JOUR ID - citeulike:1495980 L3 - citeulike-article-id:1495980 TI - A model for the interaction of two chemicals JF - Journal of Theoretical Biology VL - 238 IS - 3 SP - 652 EP - 656 N2 - We describe a method for studying the interaction of two anesthetic agents, Morphine and Midazolam, acting simultaneously in the same individual. Representing the levels of the two chemicals by diffusion processes, we assume their interaction is governed by a linear combination of the separate components. Pharmacological data is used to estimate the model parameters and, in particular, to determine the coefficient in the linear combination. This leads to the conclusion that the two chemicals have a counteractive effect. KW - biorefs KW - reaction-diffusion AU - Sen, Pali AU - Bell, Denis PY - 2006/02/07/ UR - http://dx.doi.org/10.1016/j.jtbi.2005.06.013 ER -