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A near-infrared fluorescent calcium probe: a new tool for intracellular multicolour Ca2+ imaging

by: Akihiro Matsui, Keitaro Umezawa, Yutaka Shindo, Tomohiko Fujii, Daniel Citterio, Kotaro Oka, Koji Suzuki
Chem. Commun., Vol. 47, No. 37. (2011), pp. 10407-10409, doi:10.1039/c1cc14045k  Key: citeulike:12010602

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Abstract

We report a novel near-infrared fluorescent calcium probe (KFCA), which has good optical properties such as intense NIR fluorescence emission (670 nm, QY: 0.24), excellent ON/OFF ratio (120-fold), and good wavelength-compatibility with visible-light-emissive fluorophores (Fluo-4, DsRed2), and which is applicable for real-time dual-colour intracellular Ca2+ imaging.


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