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A Simulation Testbed for the Study of Multicellular Development: The Multiple Mechanisms of Morphogenesis |
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AbstractThis paper presents a simulation framework and computational testbed for studying multicellular pattern formation. The approach combines several developmental mechanisms (chemical, mechanical, genetic and electrical) known to be important for biological pattern formation. The mechanisms are present in an environment containing discrete cells which are capable of independent movement (cell migration). Experience with the testbed indicates that the interactions between the developmental...
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