The centrosome in vertebrates: more than a microtubule-organizing center Export

@article{citeulike:6059727, abstract = {The somatic cells of all higher animals contain a single minute organelle called the centrosome. For years, the functions of the centrosome were thought to revolve around its ability to nucleate and organize the various microtubule arrays seen in interphase and mitosis. But the centrosome is more than just a microtubule-organizing center. Recent work reveals that this organelle is essential for cell-cycle progression and that this requirement is independent of its ability to organize microtubules. Here, we review the various functions attributed to the centrosome and ask which are essential for the survival and reproduction of the cell, the organism, or both.}, author = {Rieder, C.}, citeulike-article-id = {6059727}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/S0962-8924(01)02085-2}, citeulike-linkout-1 = {http://linkinghub.elsevier.com/retrieve/pii/S0962-8924(01)02085-2}, day = {1}, doi = {10.1016/S0962-8924(01)02085-2}, issn = {09628924}, journal = {Trends in Cell Biology}, keywords = {blood, cell, centrosome, no, red}, month = {October}, number = {10}, pages = {413--419}, posted-at = {2009-11-03 10:51:01}, priority = {2}, title = {The centrosome in vertebrates: more than a microtubule-organizing center}, url = {http://dx.doi.org/10.1016/S0962-8924(01)02085-2}, volume = {11}, year = {2001} }

TY - JOUR ID - citeulike:6059727 L3 - citeulike-article-id:6059727 N2 - The somatic cells of all higher animals contain a single minute organelle called the centrosome. For years, the functions of the centrosome were thought to revolve around its ability to nucleate and organize the various microtubule arrays seen in interphase and mitosis. But the centrosome is more than just a microtubule-organizing center. Recent work reveals that this organelle is essential for cell-cycle progression and that this requirement is independent of its ability to organize microtubules. Here, we review the various functions attributed to the centrosome and ask which are essential for the survival and reproduction of the cell, the organism, or both. IS - 10 JF - Trends in Cell Biology SN - 09628924 EP - 419 TI - The centrosome in vertebrates: more than a microtubule-organizing center VL - 11 SP - 413 KW - blood KW - cell KW - centrosome KW - no KW - red AU - Rieder, C PY - 2001/10/01/ UR - http://dx.doi.org/10.1016/S0962-8924(01)02085-2 ER -