Patterning of embryonic blood vessels Export

@article{citeulike:3450956, abstract = {Morphometric methods were developed to characterize the geometry of vascular patterns in avian and murine embryos. By using these methods, we found that networks of blood vessels formed during vasculogenesis share similar geometric properties (i.e., mean blood vessel diameters and avascular space diameters) regardless of developmental stage, location, or species in which they form. We also found that endothelial cell density within a unit area of an embryonic vasculature could be used to accurately distinguish between a small diameter, capillary-like vascular network (low endothelial cell density) and a large diameter, presinusoidal network (high endothelial cell density). Furthermore, we show that endothelial cell size remains constant in small and large diameter vessels, indicating that increased endothelial cell size is not the basis for diversity in vessel diameter. These observations serve as a foundation for future studies seeking to evaluate the effects of agents or genetic mutations on aspects of vasculogenesis. Developmental Dynamics 228:21-29, 2003. {\copyright} 2003 Wiley-Liss, Inc.}, address = {Cardiovascular Developmental Biology Center, Department of Cell Biology and Anatomy, Medical University of South Carolina, Charleston, South Carolina; Department of Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City, Kansas}, author = {Larue, Amanda C. and Mironov, Vladimir A. and Argraves, Scott W. and Czir\'{o}k, Andr\'{a}s and Fleming, Paul A. and Drake, Christopher J.}, citeulike-article-id = {3450956}, citeulike-linkout-0 = {http://dx.doi.org/10.1002/dvdy.10339}, citeulike-linkout-1 = {http://www3.interscience.wiley.com/cgi-bin/abstract/104548259/ABSTRACT}, doi = {10.1002/dvdy.10339}, journal = {Developmental Dynamics}, keywords = {cpm, vasculogenesis}, number = {1}, pages = {21--29}, posted-at = {2008-10-26 00:01:22}, priority = {2}, title = {Patterning of embryonic blood vessels}, url = {http://dx.doi.org/10.1002/dvdy.10339}, volume = {228}, year = {2003} }

TY - JOUR ID - citeulike:3450956 L3 - citeulike-article-id:3450956 N2 - Morphometric methods were developed to characterize the geometry of vascular patterns in avian and murine embryos. By using these methods, we found that networks of blood vessels formed during vasculogenesis share similar geometric properties (i.e., mean blood vessel diameters and avascular space diameters) regardless of developmental stage, location, or species in which they form. We also found that endothelial cell density within a unit area of an embryonic vasculature could be used to accurately distinguish between a small diameter, capillary-like vascular network (low endothelial cell density) and a large diameter, presinusoidal network (high endothelial cell density). Furthermore, we show that endothelial cell size remains constant in small and large diameter vessels, indicating that increased endothelial cell size is not the basis for diversity in vessel diameter. These observations serve as a foundation for future studies seeking to evaluate the effects of agents or genetic mutations on aspects of vasculogenesis. Developmental Dynamics 228:21-29, 2003. © 2003 Wiley-Liss, Inc. IS - 1 JF - Developmental Dynamics AD - Cardiovascular Developmental Biology Center, Department of Cell Biology and Anatomy, Medical University of South Carolina, Charleston, South Carolina; Department of Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City, Kansas EP - 29 TI - Patterning of embryonic blood vessels VL - 228 SP - 21 KW - cpm KW - vasculogenesis AU - Larue, Amanda AU - Mironov, Vladimir AU - Argraves, Scott AU - Czirók, András AU - Fleming, Paul AU - Drake, Christopher PY - 2003/// UR - http://dx.doi.org/10.1002/dvdy.10339 ER -