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A strategy for integrative computational physiology. Export

Physiology (Bethesda, Md.), Vol. 20 (October 2005), pp. 316-325.

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physiome

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Organ function (the heart beat for example) can only be understood through knowledge of molecular and cellular processes within the constraints of structure-function relations at the tissue level. A quantitative modeling framework that can deal with these multiscale issues is described here under the banner of the International Union of Physiological Sciences Physiome Project.


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