Neuroimaging Characteristics of Patients with Focal Hand Dystonia. Export

@article{citeulike:4295717, abstract = {Narrative Review: Advances in structural and functional imaging have provided both scientists and clinicians with information about the neural mechanisms underlying focal hand dystonia (FHd), a motor disorder associated with aberrant posturing and patterns of muscle contraction specific to movements of the hand. Consistent with the hypothesis that FHd is the result of reorganization in cortical fields, studies in neuroimaging have confirmed alterations in the topography and response properties of somatosensory and motor areas of the brain. Noninvasive stimulation of these regions also demonstrates that FHd may be due to reductions in inhibition between competing sensory and motor representations. Compromises in neuroanatomical structure, such as white matter density and gray matter volume, have also been identified through neuroimaging methods. These advances in neuroimaging have provided clinicians with an expanded understanding of the changes in the brain that contribute to FHd. These findings should provide a foundation for the development of retraining paradigms focused on reversing overlapping sensory representations and interactions between brain regions in patients with FHd. Continued collaborations between health professionals who treat FHd and research scientists who examine the brain using neuroimaging tools are imperative for answering difficult questions about patients with specific movement disorders.}, author = {Hinkley, Leighton B N B. and Webster, Rebecca L L. and Byl, Nancy N N. and Nagarajan, Srikantan S S.}, citeulike-article-id = {4295717}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.jht.2008.11.002}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/19217255}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=19217255}, day = {11}, doi = {10.1016/j.jht.2008.11.002}, issn = {0894-1130}, journal = {Journal of hand therapy : official journal of the American Society of Hand Therapists}, keywords = {disorder, dystonia, meg, motor}, month = {February}, posted-at = {2009-04-10 02:45:18}, priority = {2}, title = {Neuroimaging Characteristics of Patients with Focal Hand Dystonia.}, url = {http://dx.doi.org/10.1016/j.jht.2008.11.002}, year = {2009} }

TY - JOUR ID - citeulike:4295717 L3 - citeulike-article-id:4295717 N2 - Narrative Review: Advances in structural and functional imaging have provided both scientists and clinicians with information about the neural mechanisms underlying focal hand dystonia (FHd), a motor disorder associated with aberrant posturing and patterns of muscle contraction specific to movements of the hand. Consistent with the hypothesis that FHd is the result of reorganization in cortical fields, studies in neuroimaging have confirmed alterations in the topography and response properties of somatosensory and motor areas of the brain. Noninvasive stimulation of these regions also demonstrates that FHd may be due to reductions in inhibition between competing sensory and motor representations. Compromises in neuroanatomical structure, such as white matter density and gray matter volume, have also been identified through neuroimaging methods. These advances in neuroimaging have provided clinicians with an expanded understanding of the changes in the brain that contribute to FHd. These findings should provide a foundation for the development of retraining paradigms focused on reversing overlapping sensory representations and interactions between brain regions in patients with FHd. Continued collaborations between health professionals who treat FHd and research scientists who examine the brain using neuroimaging tools are imperative for answering difficult questions about patients with specific movement disorders. JF - Journal of hand therapy : official journal of the American Society of Hand Therapists SN - 0894-1130 TI - Neuroimaging Characteristics of Patients with Focal Hand Dystonia. KW - disorder KW - dystonia KW - meg KW - motor AU - Hinkley, Leighton B N AU - Webster, Rebecca L AU - Byl, Nancy N AU - Nagarajan, Srikantan S PY - 2009/02/11/ UR - http://dx.doi.org/10.1016/j.jht.2008.11.002 ER -