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Plagiarized bacterial genes in the human book of life Export

by: Chris P. Ponting
Trends in Genetics, Vol. 17, No. 5. (1 May 2001), pp. 235-237.

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bacterial eukaryal evolution genomics

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The initial analysis of the human genome draft sequence reveals that our `book of life' is multi-authored. A small but significant proportion of our genes owes their heritage not to antecedent eukaryotes but instead to bacteria. The publicly funded Human Genome Project study indicates that about 0.5% of all human genes were copied into the genome from bacterial sources. Detailed sequence analyses point to these `horizontal gene transfer' events having occurred relatively recently. So how did the human `book of life' evolve to be a chimaera, part animal and part bacterium? And what was the probable evolutionary impact of such gene plagiarism?


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