Degeneration of nuclei and mitochondria in human hairs. Export

@article{citeulike:4116670, abstract = {It is generally accepted that nuclei degrade in developing hair shafts but the point at which such occurs has not been investigated. The fate of mitochondria in the keratinizing hair shaft has been less clear. This study uses transmission electron microscopy to investigate when nuclei and mitochondria are no longer visible in the developing hair shaft. Serial sections were obtained from anagen head hairs absent follicles in order to determine the sequence of degradation of nuclei and mitochondria in the hair shaft by starting at the root bulb and proceeding toward the hair tip. It was demonstrated that nuclei and mitochondria become invisible in the keratinizing hair shaft at about the same time. This was found to occur fairly early in the process at the level of the hair shaft where the hair cuticle becomes permanent.}, author = {Linch, Charles A.}, citeulike-article-id = {4116670}, citeulike-linkout-0 = {http://dx.doi.org/10.1111/j.1556-4029.2008.00972.x}, citeulike-linkout-1 = {http://www.ingentaconnect.com/content/bsc/jfo/2009/00000054/00000002/art00012}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/19187450}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=19187450}, doi = {10.1111/j.1556-4029.2008.00972.x}, issn = {1556-4029}, journal = {Journal of forensic sciences}, keywords = {forensic, hair, hair-dna, mtdna, mtpcr}, month = {March}, number = {2}, pages = {346--349}, posted-at = {2009-11-06 22:02:27}, priority = {2}, publisher = {Blackwell Publishing}, title = {Degeneration of nuclei and mitochondria in human hairs.}, url = {http://dx.doi.org/10.1111/j.1556-4029.2008.00972.x}, volume = {54}, year = {2009} }

TY - JOUR ID - citeulike:4116670 L3 - citeulike-article-id:4116670 N2 - It is generally accepted that nuclei degrade in developing hair shafts but the point at which such occurs has not been investigated. The fate of mitochondria in the keratinizing hair shaft has been less clear. This study uses transmission electron microscopy to investigate when nuclei and mitochondria are no longer visible in the developing hair shaft. Serial sections were obtained from anagen head hairs absent follicles in order to determine the sequence of degradation of nuclei and mitochondria in the hair shaft by starting at the root bulb and proceeding toward the hair tip. It was demonstrated that nuclei and mitochondria become invisible in the keratinizing hair shaft at about the same time. This was found to occur fairly early in the process at the level of the hair shaft where the hair cuticle becomes permanent. IS - 2 JF - Journal of forensic sciences SN - 1556-4029 EP - 349 TI - Degeneration of nuclei and mitochondria in human hairs. PB - Blackwell Publishing VL - 54 SP - 346 KW - forensic KW - hair KW - hair-dna KW - mtdna KW - mtpcr AU - Linch, Charles PY - 2009/03// UR - http://dx.doi.org/10.1111/j.1556-4029.2008.00972.x ER -