The thermal grill illusion: unmasking the burn of cold pain Export

@article{citeulike:3575832, abstract = {In Thunberg's thermal grill illusion, first demonstrated in 1896, a sensation of strong, often painful heat is elicited by touching interlaced warm and cool bars to the skin. Neurophysiological recordings from two classes of ascending spinothalamic tract neurons that are sensitive to innocuous or noxious cold showed differential responses to the grill. On the basis of these results, a simple model of central disinhibition, or unmasking, predicted a quantitative correspondence between grill-evoked pain and cold-evoked pain, which was verified psychophysically. This integration of pain and temperature can explain the thermal grill illusion and the burning sensation of cold pain and may also provide a basis for the cold-evoked, burning pain of the classic thalamic pain syndrome. 10.1126/science.8023144}, author = {Craig, A. D. and Bushnell, M. C.}, citeulike-article-id = {3575832}, citeulike-linkout-0 = {http://dx.doi.org/10.1126/science.8023144}, citeulike-linkout-1 = {http://www.sciencemag.org/cgi/content/abstract/265/5169/252}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/8023144}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=8023144}, day = {8}, doi = {10.1126/science.8023144}, issn = {0036-8075}, journal = {Science}, keywords = {pain}, month = {July}, number = {5169}, pages = {252--255}, posted-at = {2008-11-18 21:38:46}, priority = {2}, title = {The thermal grill illusion: unmasking the burn of cold pain}, url = {http://dx.doi.org/10.1126/science.8023144}, volume = {265}, year = {1994} }

TY - JOUR ID - citeulike:3575832 L3 - citeulike-article-id:3575832 N2 - In Thunberg's thermal grill illusion, first demonstrated in 1896, a sensation of strong, often painful heat is elicited by touching interlaced warm and cool bars to the skin. Neurophysiological recordings from two classes of ascending spinothalamic tract neurons that are sensitive to innocuous or noxious cold showed differential responses to the grill. On the basis of these results, a simple model of central disinhibition, or unmasking, predicted a quantitative correspondence between grill-evoked pain and cold-evoked pain, which was verified psychophysically. This integration of pain and temperature can explain the thermal grill illusion and the burning sensation of cold pain and may also provide a basis for the cold-evoked, burning pain of the classic thalamic pain syndrome. 10.1126/science.8023144 IS - 5169 JF - Science SN - 0036-8075 EP - 255 TI - The thermal grill illusion: unmasking the burn of cold pain VL - 265 SP - 252 KW - pain AU - Craig, AD AU - Bushnell, MC PY - 1994/07/08/ UR - http://dx.doi.org/10.1126/science.8023144 ER -