Relationship between finger movement rate and functional magnetic resonance signal change in human primary motor cortex. Export

@article{citeulike:4488782, abstract = {Functional magnetic resonance imaging (FMRI) is a noninvasive technique for mapping regional brain changes in response to sensory, motor, or cognitive activation tasks. Interpretation of these activation experiments may be confounded by more elementary task parameters, such as stimulus presentation or movement rates. We examined the effect of movement rate on the FMRI response recorded from the contralateral primary motor cortex. Four right-handed healthy subjects performed flexion-extension movements of digits 2-5 of the right hand at rates of 1, 2, 3, 4, or 5 Hz. Results of this study indicated a positive linear relationship between movement rate and FMRI signal change. Additionally, the number of voxels demonstrating functional activity increased significantly with faster movement rates. The magnitude of the signal change at each movement rate remained constant over the course of three 8-min scanning series. These findings are similar to those of previous rate studies of the visual and auditory system performed with positron emission tomography (PET) and FMRI.}, author = {Rao, S. M. and Bandettini, P. A. and Binder, J. R. and Bobholz, J. A. and Hammeke, T. A. and Stein, E. A. and Hyde, J. S.}, citeulike-article-id = {4488782}, citeulike-linkout-0 = {http://dx.doi.org/10.1097/00004647-199611000-00020}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/8898698}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=8898698}, doi = {10.1097/00004647-199611000-00020}, issn = {0271-678X}, journal = {Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism}, keywords = {fmri, variability}, month = {November}, number = {6}, pages = {1250--1254}, posted-at = {2009-05-07 19:47:30}, priority = {2}, title = {Relationship between finger movement rate and functional magnetic resonance signal change in human primary motor cortex.}, url = {http://dx.doi.org/10.1097/00004647-199611000-00020}, volume = {16}, year = {1996} }

TY - JOUR ID - citeulike:4488782 L3 - citeulike-article-id:4488782 N2 - Functional magnetic resonance imaging (FMRI) is a noninvasive technique for mapping regional brain changes in response to sensory, motor, or cognitive activation tasks. Interpretation of these activation experiments may be confounded by more elementary task parameters, such as stimulus presentation or movement rates. We examined the effect of movement rate on the FMRI response recorded from the contralateral primary motor cortex. Four right-handed healthy subjects performed flexion-extension movements of digits 2-5 of the right hand at rates of 1, 2, 3, 4, or 5 Hz. Results of this study indicated a positive linear relationship between movement rate and FMRI signal change. Additionally, the number of voxels demonstrating functional activity increased significantly with faster movement rates. The magnitude of the signal change at each movement rate remained constant over the course of three 8-min scanning series. These findings are similar to those of previous rate studies of the visual and auditory system performed with positron emission tomography (PET) and FMRI. IS - 6 JF - Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism SN - 0271-678X EP - 1254 TI - Relationship between finger movement rate and functional magnetic resonance signal change in human primary motor cortex. VL - 16 SP - 1250 KW - fmri KW - variability AU - Rao, SM AU - Bandettini, PA AU - Binder, JR AU - Bobholz, JA AU - Hammeke, TA AU - Stein, EA AU - Hyde, JS PY - 1996/11// UR - http://dx.doi.org/10.1097/00004647-199611000-00020 ER -