Homology-based modelling of targets for rational drug design. Export

@article{wieman:04, abstract = {The current status in rational drug design using homology-based models is discussed, with focus on template selection, model building, model verification and strategies for drug design based on model structures. A novel approach for identification of unique binding site features from homology-based models, Protein Alpha Shape Similarity Analysis (PASSA) is described.}, address = {Department of Cancer Research and Molecular Medicine, Faculty of Medicine, MTFS, Norwegian University of Science and Technology, N-7489 Trondheim.}, author = {Wieman, H. and T{\o}ndel, K. and Anderssen, E. and Drabl{\o}s, F.}, citeulike-article-id = {479609}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/15379646}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=15379646}, issn = {1389-5575}, journal = {Mini Rev Med Chem}, keywords = {design, homology, ligand, review}, month = {September}, number = {7}, pages = {793--804}, posted-at = {2009-01-09 02:54:57}, priority = {0}, title = {Homology-based modelling of targets for rational drug design.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/15379646}, volume = {4}, year = {2004} }

TY - JOUR ID - wieman:04 L3 - citeulike-article-id:479609 N2 - The current status in rational drug design using homology-based models is discussed, with focus on template selection, model building, model verification and strategies for drug design based on model structures. A novel approach for identification of unique binding site features from homology-based models, Protein Alpha Shape Similarity Analysis (PASSA) is described. IS - 7 JF - Mini Rev Med Chem SN - 1389-5575 AD - Department of Cancer Research and Molecular Medicine, Faculty of Medicine, MTFS, Norwegian University of Science and Technology, N-7489 Trondheim. EP - 804 TI - Homology-based modelling of targets for rational drug design. VL - 4 SP - 793 KW - design KW - homology KW - ligand KW - review AU - Wieman, H AU - Tøndel, K AU - Anderssen, E AU - Drabløs, F PY - 2004/09// UR - http://view.ncbi.nlm.nih.gov/pubmed/15379646 ER -