Ploidy and the Causes of Genomic Evolution Export

@article{citeulike:5800905, abstract = {Genomes vary dramatically in size and in content. This variation is driven in part by numerous polyploidization events that have happened over the course of eukaryotic evolution. Experimental evolution studies, primarily using the yeast Saccharomyces cerevisiae, provide insights into the immediate fitness effects of ploidy mutations, the ability of organisms of different ploidy levels to mask deleterious mutations, the impact of ploidy on rates of adaptation, and the relative roles of selection versus drift in shaping ploidy evolution. We review these experimental evolution studies and present new data on differences in maximal growth rate for cells of different ploidy levels. 10.1093/jhered/esp057}, author = {Gerstein, Aleeza C. and Otto, Sarah P.}, citeulike-article-id = {5800905}, citeulike-linkout-0 = {http://dx.doi.org/10.1093/jhered/esp057}, citeulike-linkout-1 = {http://jhered.oxfordjournals.org/content/100/5/571.abstract}, citeulike-linkout-2 = {http://jhered.oxfordjournals.org/content/100/5/571.full.pdf}, citeulike-linkout-3 = {http://view.ncbi.nlm.nih.gov/pubmed/19625454}, citeulike-linkout-4 = {http://www.hubmed.org/display.cgi?uids=19625454}, day = {1}, doi = {10.1093/jhered/esp057}, issn = {1465-7333}, journal = {J Hered}, keywords = {diploid, diploidy, genomic\_evolution, haploid, haploidy, ploidy, polyploidization}, month = {September}, number = {5}, pages = {571--581}, posted-at = {2009-09-29 04:15:38}, priority = {0}, title = {Ploidy and the Causes of Genomic Evolution}, url = {http://dx.doi.org/10.1093/jhered/esp057}, volume = {100}, year = {2009} }

TY - JOUR ID - citeulike:5800905 L3 - citeulike-article-id:5800905 N2 - Genomes vary dramatically in size and in content. This variation is driven in part by numerous polyploidization events that have happened over the course of eukaryotic evolution. Experimental evolution studies, primarily using the yeast Saccharomyces cerevisiae, provide insights into the immediate fitness effects of ploidy mutations, the ability of organisms of different ploidy levels to mask deleterious mutations, the impact of ploidy on rates of adaptation, and the relative roles of selection versus drift in shaping ploidy evolution. We review these experimental evolution studies and present new data on differences in maximal growth rate for cells of different ploidy levels. 10.1093/jhered/esp057 IS - 5 JF - J Hered SN - 1465-7333 EP - 581 TI - Ploidy and the Causes of Genomic Evolution VL - 100 SP - 571 KW - diploid KW - diploidy KW - genomic_evolution KW - haploid KW - haploidy KW - ploidy KW - polyploidization AU - Gerstein, Aleeza AU - Otto, Sarah PY - 2009/09/01/t UR - http://dx.doi.org/10.1093/jhered/esp057 ER -