DNA tests probe the genomic ancestry of Brazilians. Export

@article{citeulike:5806439, abstract = {We review studies from our laboratories using different molecular tools to characterize the ancestry of Brazilians in reference to their Amerindian, European and African roots. Initially we used uniparental DNA markers to investigate the contribution of distinct Y chromosome and mitochondrial DNA lineages to present-day populations. High levels of genetic admixture and strong directional mating between European males and Amerindian and African females were unraveled. We next analyzed different types of biparental autosomal polymorphisms. Especially useful was a set of 40 insertion-deletion polymorphisms (indels) that when studied worldwide proved exquisitely sensitive in discriminating between Amerindians, Europeans and Sub-Saharan Africans. When applied to the study of Brazilians these markers confirmed extensive genomic admixture, but also demonstrated a strong imprint of the massive European immigration wave in the 19th and 20th centuries. The high individual ancestral variability observed suggests that each Brazilian has a singular proportion of Amerindian, European and African ancestries in his mosaic genome. In Brazil, one cannot predict the color of persons from their genomic ancestry nor the opposite. Brazilians should be assessed on a personal basis, as 190 million human beings, and not as members of color groups.}, author = {Pena, S. D. and Bastos-Rodrigues, L. and Pimenta, J. R. and Bydlowski, S. P.}, citeulike-article-id = {5806439}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/19738982}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=19738982}, day = {11}, issn = {1414-431X}, journal = {Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas / Sociedade Brasileira de Biofisica ... [et al.]}, keywords = {ancestry, brazilians, dna\_tests, genome, genomic\_ancestry}, month = {September}, posted-at = {2009-09-20 05:48:43}, priority = {0}, title = {DNA tests probe the genomic ancestry of Brazilians.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/19738982}, year = {2009} }

TY - JOUR ID - citeulike:5806439 L3 - citeulike-article-id:5806439 N2 - We review studies from our laboratories using different molecular tools to characterize the ancestry of Brazilians in reference to their Amerindian, European and African roots. Initially we used uniparental DNA markers to investigate the contribution of distinct Y chromosome and mitochondrial DNA lineages to present-day populations. High levels of genetic admixture and strong directional mating between European males and Amerindian and African females were unraveled. We next analyzed different types of biparental autosomal polymorphisms. Especially useful was a set of 40 insertion-deletion polymorphisms (indels) that when studied worldwide proved exquisitely sensitive in discriminating between Amerindians, Europeans and Sub-Saharan Africans. When applied to the study of Brazilians these markers confirmed extensive genomic admixture, but also demonstrated a strong imprint of the massive European immigration wave in the 19th and 20th centuries. The high individual ancestral variability observed suggests that each Brazilian has a singular proportion of Amerindian, European and African ancestries in his mosaic genome. In Brazil, one cannot predict the color of persons from their genomic ancestry nor the opposite. Brazilians should be assessed on a personal basis, as 190 million human beings, and not as members of color groups. JF - Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas / Sociedade Brasileira de Biofisica ... [et al.] SN - 1414-431X TI - DNA tests probe the genomic ancestry of Brazilians. KW - ancestry KW - brazilians KW - dna_tests KW - genome KW - genomic_ancestry AU - Pena, SD AU - Bastos-Rodrigues, L AU - Pimenta, JR AU - Bydlowski, SP PY - 2009/09/11/ UR - http://view.ncbi.nlm.nih.gov/pubmed/19738982 ER -