The beta gamma subunits of GTP-binding proteins activate the muscarinic K+ channel in heart. Export

@article{citeulike:406633, abstract = {Subunits of guanine nucleotide regulatory proteins purified from bovine cerebral cortex were used to perfuse the intracellular surface of excised patches of chick embryonic atrial cells. Single-channel current measurements unexpectedly indicate that the beta gamma, and not the alpha subunits, are responsible for activating the muscarinic-gated potassium channel.}, author = {Logothetis, D. E. and Kurachi, Y. and Galper, J. and Neer, E. J. and Clapham, D. E.}, citeulike-article-id = {406633}, citeulike-linkout-0 = {http://dx.doi.org/10.1038/325321a0}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/2433589}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=2433589}, doi = {10.1038/325321a0}, issn = {0028-0836}, journal = {Nature}, keywords = {5-o-3-thiotriphosphate, amp, analogs, channel, conductivity, derivative, electric, embryo, gtp-binding, guanosine, guanylyl, imidodiphosphate, ion, macromolecular, magnesium, muscarinic, potassium, receptor, relationship, structure-activity, thionucleotide, triphosphate}, number = {6102}, pages = {321--326}, posted-at = {2005-11-23 19:50:53}, priority = {2}, title = {The beta gamma subunits of GTP-binding proteins activate the muscarinic K+ channel in heart.}, url = {http://dx.doi.org/10.1038/325321a0}, volume = {325}, year = {1987} }

TY - JOUR ID - citeulike:406633 L3 - citeulike-article-id:406633 N2 - Subunits of guanine nucleotide regulatory proteins purified from bovine cerebral cortex were used to perfuse the intracellular surface of excised patches of chick embryonic atrial cells. Single-channel current measurements unexpectedly indicate that the beta gamma, and not the alpha subunits, are responsible for activating the muscarinic-gated potassium channel. IS - 6102 JF - Nature SN - 0028-0836 EP - 326 TI - The beta gamma subunits of GTP-binding proteins activate the muscarinic K+ channel in heart. VL - 325 SP - 321 KW - 5-o-3-thiotriphosphate KW - amp KW - analogs KW - channel KW - conductivity KW - derivative KW - electric KW - embryo KW - gtp-binding KW - guanosine KW - guanylyl KW - imidodiphosphate KW - ion KW - macromolecular KW - magnesium KW - muscarinic KW - potassium KW - receptor KW - relationship KW - structure-activity KW - thionucleotide KW - triphosphate AU - Logothetis, DE AU - Kurachi, Y AU - Galper, J AU - Neer, EJ AU - Clapham, DE PY - 1987///8 UR - http://dx.doi.org/10.1038/325321a0 ER -