Cloning the gene for an inherited human disorder--chronic granulomatous disease--on the basis of its chromosomal location. Export

@article{citeulike:2961836, abstract = {The gene that is abnormal in the X-linked form of the phagocytic disorder chronic granulomatous disease has been cloned without reference to a specific protein by relying on its chromosomal map position. The transcript of the gene is expressed in the phagocytic lineage of haematopoietic cells and is absent or structurally abnormal in four patients with the disorder. The nucleotide sequence of complementary DNA clones predicts a polypeptide of at least 468 amino acids with no homology to proteins described previously.}, author = {Royer-Pokora, B. and Kunkel, L. M. and Monaco, A. P. and Goff, S. C. and Newburger, P. E. and Baehner, R. L. and Cole, F. S. and Curnutte, J. T. and Orkin, S. H.}, citeulike-article-id = {2961836}, citeulike-linkout-0 = {http://dx.doi.org/10.1038/322032a0}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/2425263}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=2425263}, doi = {10.1038/322032a0}, issn = {0028-0836}, journal = {Nature}, keywords = {immunodeficiency}, number = {6074}, pages = {32--38}, posted-at = {2008-07-04 05:25:26}, priority = {2}, title = {Cloning the gene for an inherited human disorder--chronic granulomatous disease--on the basis of its chromosomal location.}, url = {http://dx.doi.org/10.1038/322032a0}, volume = {322}, year = {1986} }

TY - JOUR ID - citeulike:2961836 L3 - citeulike-article-id:2961836 N2 - The gene that is abnormal in the X-linked form of the phagocytic disorder chronic granulomatous disease has been cloned without reference to a specific protein by relying on its chromosomal map position. The transcript of the gene is expressed in the phagocytic lineage of haematopoietic cells and is absent or structurally abnormal in four patients with the disorder. The nucleotide sequence of complementary DNA clones predicts a polypeptide of at least 468 amino acids with no homology to proteins described previously. IS - 6074 JF - Nature SN - 0028-0836 EP - 38 TI - Cloning the gene for an inherited human disorder--chronic granulomatous disease--on the basis of its chromosomal location. VL - 322 SP - 32 KW - immunodeficiency AU - Royer-Pokora, B AU - Kunkel, LM AU - Monaco, AP AU - Goff, SC AU - Newburger, PE AU - Baehner, RL AU - Cole, FS AU - Curnutte, JT AU - Orkin, SH PY - 1986///9 UR - http://dx.doi.org/10.1038/322032a0 ER -