General principles and pharmacology of biologics in inflammatory bowel disease.

@article{citeulike:3016181, abstract = {The pharmacology of each biologic agent is important regarding the dose required to achieve benefits, duration of therapeutic effect, and the induction of immunogenicity. Comprehension of the individual pharmacology, pharmacodynamics, and pharmacokinetics, in addition to the impact of concomitant immunomodulation on immunogenicity allows optimization of each biologic agent in the appropriate inductive or maintenance setting of IBD.}, address = {Division of Gastroenterology, Department of Medicine, University of Chicago Hospitals, MC 4076, 5841 South Maryland Avenue, Chicago, IL 60637, USA.}, author = {Kozuch, P. L. and Hanauer, S. B. }, citeulike-article-id = {3016181}, doi = {http://dx.doi.org/10.1016/j.gtc.2006.09.005}, issn = {0889-8553}, journal = {Gastroenterology clinics of North America}, keywords = {ibd}, month = {December}, number = {4}, pages = {757--773}, posted-at = {2008-07-20 02:17:36}, priority = {2}, title = {General principles and pharmacology of biologics in inflammatory bowel disease.}, url = {http://dx.doi.org/10.1016/j.gtc.2006.09.005}, volume = {35}, year = {2006} }

TY - JOUR ID - citeulike:3016181 L3 - citeulike-article-id:3016181 TI - General principles and pharmacology of biologics in inflammatory bowel disease. JF - Gastroenterology clinics of North America VL - 35 IS - 4 SP - 757 EP - 773 AD - Division of Gastroenterology, Department of Medicine, University of Chicago Hospitals, MC 4076, 5841 South Maryland Avenue, Chicago, IL 60637, USA. SN - 0889-8553 N2 - The pharmacology of each biologic agent is important regarding the dose required to achieve benefits, duration of therapeutic effect, and the induction of immunogenicity. Comprehension of the individual pharmacology, pharmacodynamics, and pharmacokinetics, in addition to the impact of concomitant immunomodulation on immunogenicity allows optimization of each biologic agent in the appropriate inductive or maintenance setting of IBD. KW - ibd AU - Kozuch, PL AU - Hanauer, SB PY - 2006/12// UR - http://dx.doi.org/10.1016/j.gtc.2006.09.005 ER -