A homozygous frameshift mutation in the mouse Flg gene facilitates enhanced percutaneous allergen priming Export

@article{citeulike:4442504, abstract = {Irwin McLean and colleagues show that the flaky tail mouse mutant has a frameshift mutation in the gene encoding filaggrin. Topical application of allergen to flaky tail mice results in skin inflammation and enhanced cutaneous allergen priming, shedding light on the mechanisms underlying filaggrin-related atopic disease.}, author = {Fallon, Padraic G. and Sasaki, Takashi and Sandilands, Aileen and Campbell, Linda E. and Saunders, Sean P. and Mangan, Niamh E. and Callanan, John J. and Kawasaki, Hiroshi and Shiohama, Aiko and Kubo, Akiharu and Sundberg, John P. and Presland, Richard B. and Fleckman, Philip and Shimizu, Nobuyoshi and Kudoh, Jun and Irvine, Alan D. and Amagai, Masayuki and Mclean, Irwin W. H.}, citeulike-article-id = {4442504}, citeulike-linkout-0 = {http://dx.doi.org/10.1038/ng.358}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/19349982}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=19349982}, day = {06}, doi = {10.1038/ng.358}, issn = {1061-4036}, journal = {Nature Genetics}, keywords = {eczema}, month = {April}, number = {5}, pages = {602--608}, posted-at = {2009-06-03 04:27:52}, priority = {2}, publisher = {Nature Publishing Group}, title = {A homozygous frameshift mutation in the mouse Flg gene facilitates enhanced percutaneous allergen priming}, url = {http://dx.doi.org/10.1038/ng.358}, volume = {41}, year = {2009} }

TY - JOUR ID - citeulike:4442504 L3 - citeulike-article-id:4442504 N2 - Irwin McLean and colleagues show that the flaky tail mouse mutant has a frameshift mutation in the gene encoding filaggrin. Topical application of allergen to flaky tail mice results in skin inflammation and enhanced cutaneous allergen priming, shedding light on the mechanisms underlying filaggrin-related atopic disease. IS - 5 JF - Nature Genetics SN - 1061-4036 EP - 608 TI - A homozygous frameshift mutation in the mouse Flg gene facilitates enhanced percutaneous allergen priming PB - Nature Publishing Group VL - 41 SP - 602 KW - eczema AU - Fallon, Padraic AU - Sasaki, Takashi AU - Sandilands, Aileen AU - Campbell, Linda AU - Saunders, Sean AU - Mangan, Niamh AU - Callanan, John AU - Kawasaki, Hiroshi AU - Shiohama, Aiko AU - Kubo, Akiharu AU - Sundberg, John AU - Presland, Richard AU - Fleckman, Philip AU - Shimizu, Nobuyoshi AU - Kudoh, Jun AU - Irvine, Alan AU - Amagai, Masayuki AU - Mclean, Irwin PY - 2009/04/06/ UR - http://dx.doi.org/10.1038/ng.358 ER -