Principles of nanostructure design with protein building blocks.

@article{citeulike:1326323, abstract = {Currently there is increasing interest in nanostructures and their design. Nanostructure design involves the ability to predictably manipulate the properties of the self-assembly of autonomous units. Autonomous units have preferred conformational states. The units can be synthetic material science-based or derived from functional biological macromolecules. Autonomous biological building blocks with available structures provide an extremely rich and useful resource for design. For proteins, the structural databases contain large libraries of protein molecules and their building blocks with a range of shapes, surfaces, and chemical properties. The introduction of engineered synthetic residues or short peptides into these can expand the available chemical space and enhance the desired properties. Here we focus on the principles of nanostructure design with protein building blocks. Proteins 2007. (c) 2007 Wiley-Liss, Inc.}, address = {Basic Research Program, SAIC‐Frederick, Inc., Center for Cancer Research Nanobiology Program, NCI‐Frederick, Frederick, Maryland 21702.}, author = {Tsai, Chung-Jung J. and Zheng, Jie and Zanuy, David and Haspel, Nurit and Wolfson, Haim and Alem\'{a}n, Carlos and Nussinov, Ruth }, citeulike-article-id = {1326323}, doi = {10.1002/prot.21413}, issn = {1097-0134}, journal = {Proteins}, keywords = {origami, origami-alternatives, review}, month = {April}, number = {1}, pages = {1--12}, posted-at = {2008-05-06 21:24:17}, priority = {2}, title = {Principles of nanostructure design with protein building blocks.}, url = {http://dx.doi.org/10.1002/prot.21413}, volume = {68}, year = {2007} }

TY - JOUR ID - citeulike:1326323 TI - Principles of nanostructure design with protein building blocks. JF - Proteins VL - 68 IS - 1 SP - 1 EP - 12 AD - Basic Research Program, SAIC‐Frederick, Inc., Center for Cancer Research Nanobiology Program, NCI‐Frederick, Frederick, Maryland 21702. SN - 1097-0134 N2 - Currently there is increasing interest in nanostructures and their design. Nanostructure design involves the ability to predictably manipulate the properties of the self-assembly of autonomous units. Autonomous units have preferred conformational states. The units can be synthetic material science-based or derived from functional biological macromolecules. Autonomous biological building blocks with available structures provide an extremely rich and useful resource for design. For proteins, the structural databases contain large libraries of protein molecules and their building blocks with a range of shapes, surfaces, and chemical properties. The introduction of engineered synthetic residues or short peptides into these can expand the available chemical space and enhance the desired properties. Here we focus on the principles of nanostructure design with protein building blocks. Proteins 2007. (c) 2007 Wiley-Liss, Inc. KW - origami KW - origami-alternatives KW - review AU - Tsai, Chung-Jung AU - Zheng, Jie AU - Zanuy, David AU - Haspel, Nurit AU - Wolfson, Haim AU - Alemán, Carlos AU - Nussinov, Ruth PY - 2007/04/03/ UR - http://dx.doi.org/10.1002/prot.21413 ER -