Spatially Addressable Multiprotein Nanoarrays Templated by Aptamer-Tagged DNA Nanoarchitectures

by: R Chhabra, J Sharma, Y Ke, Y Liu, S Rinker, S Lindsay, H Yan

J. Am. Chem. Soc., Vol. 129, No. 34. (29 August 2007), pp. 10304-10305.

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DOI, American Chem. Soc. Publications

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addons, addons-protein, aptamer, origami

Abstract

Abstract: Here we generalize a highly programmable strategy to self-assemble multiprotein nanoarrays with deterministic positional addressability. These protein nanoarrays were templated by aptamer-tagged DNA nanoarchitectures. Arrays of proteins with precisely controlled positions and interprotein spacings offer great potential in proteomics, tissue engineering, and medical diagnostics.

@article{Chhabra2007, abstract = {Abstract: Here we generalize a highly programmable strategy to self-assemble multiprotein nanoarrays with deterministic positional addressability. These protein nanoarrays were templated by aptamer-tagged DNA nanoarchitectures. Arrays of proteins with precisely controlled positions and interprotein spacings offer great potential in proteomics, tissue engineering, and medical diagnostics.}, address = {Department of Chemistry and Biochemistry and The Biodesign Institute, Arizona State University, Tempe, Arizona 85287}, author = {Chhabra, R. and Sharma, J. and Ke, Y. and Liu, Y. and Rinker, S. and Lindsay, S. and Yan, H. }, citeulike-article-id = {2310032}, doi = {http://dx.doi.org/10.1021/ja072410u}, journal = {J. Am. Chem. Soc.}, keywords = {addons, addons-protein, aptamer, origami}, month = {August}, number = {34}, pages = {10304--10305}, posted-at = {2008-01-31 09:20:49}, priority = {4}, title = {Spatially Addressable Multiprotein Nanoarrays Templated by Aptamer-Tagged DNA Nanoarchitectures}, url = {http://dx.doi.org/10.1021/ja072410u}, volume = {129}, year = {2007} }

RIS record

TY - JOUR ID - Chhabra2007 L3 - citeulike-article-id:2310032 TI - Spatially Addressable Multiprotein Nanoarrays Templated by Aptamer-Tagged DNA Nanoarchitectures JF - J. Am. Chem. Soc. VL - 129 IS - 34 SP - 10304 EP - 10305 AD - Department of Chemistry and Biochemistry and The Biodesign Institute, Arizona State University, Tempe, Arizona 85287 N2 - Abstract: Here we generalize a highly programmable strategy to self-assemble multiprotein nanoarrays with deterministic positional addressability. These protein nanoarrays were templated by aptamer-tagged DNA nanoarchitectures. Arrays of proteins with precisely controlled positions and interprotein spacings offer great potential in proteomics, tissue engineering, and medical diagnostics. KW - addons KW - addons-protein KW - aptamer KW - origami AU - Chhabra, R AU - Sharma, J AU - Ke, Y AU - Liu, Y AU - Rinker, S AU - Lindsay, S AU - Yan, H PY - 2007/08/29/ UR - http://dx.doi.org/10.1021/ja072410u ER -

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