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The design of a biochip: a self-assembling molecular-scale memory device

by: Bruce H Robinson, Nadrian C Seeman
Protein Eng., Vol. 1, No. 4. (1 August 1987), pp. 295-300.


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A design for a biochip memory device based on known materials and existing principles is presented. The fabrication of this memory system relies on the self-assembly of the nucleic acid junction system, which acts as the scaffolding for a molecular wire consisting of polyacetylene-like units. A molecular switch to control current is described which is based on the formation of a charge - transfer complex. A molecular-scale bit is presented which is based on oxidation - reduction potentials of metal atoms or clusters. The readable bit' which can be made of these components has a volume of 3x107 A3 and should operate at electronic speeds over short distances. 10.1093/protein/1.4.295


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