dna's surface-si [7 articles]

Abstract

Artificial DNA nanostructures1, 2 show promise for the organization of functional materials3, 4 to create nanoelectronic5 or nano-optical devices. DNA origami, in which a long single strand of DNA is folded into a shape using shorter 'staple strands'6, can display 6-nm-resolution patterns of binding sites, in principle allowing complex arrangements of carbon nanotubes, silicon nanowires, or quantum dots. However, DNA origami are synthesized in solution and uncontrolled deposition results in random arrangements; this makes it difficult to measure the properties of ...

Abstract

The application of Nucleogen , a series of novel silica gel-based anion exchangers of different pore size in the range 60–4000 Å, to analytical and large-scale high-performance liquid chromatography of a wide variety of nucleic acids is described. The influence of pore size, pH, temperature, eluting salts, bivalent metal ions, denaturing reagents and flow-rate on resolution, purity and capacity was studied. High resolution was obtained for oligonucleotides up to a chainlength of 37, natural RNSs from tRNS up to phage RNA ...

Abstract

A procedure for the purification of viroid RNA from tomato plants is described which yields up to a milligram of viroid RNA of gel electrophoretic homogeneity within 2 days. This technique is at least three times as fast as previous methods and is generally applicable to other RNA species. Plant material was homogenized and phenol extracted. In a Cs2SO4 density gradient, viroid RNA together with low-molecular-weight RNA, was separated from large single-stranded RNA, DNA, polysaccharides, polyphenols, and other compounds. The separation ...

Abstract

A new generation of plastic transistors consisting primarily of light and flexible organic materials requires new fabrication methods which combine low-temperature, solution-phase processing with precise control in the nanometer range over the component dimensions. Ultrathin silicon oxide films, which serve as gate dielectric layers in these transistors, were recently grown at room temperature from polymer precursor films by a novel layer-by-layer deposition/oxidation process. ...