The Chlamydomonas Genome Reveals the Evolution of Key Animal and Plant Functions Export

@article{citeulike:1767644, abstract = {Chlamydomonas reinhardtii is a unicellular green alga whose lineage diverged from land plants over 1 billion years ago. It is a model system for studying chloroplast-based photosynthesis, as well as the structure, assembly, and function of eukaryotic flagella (cilia), which were inherited from the common ancestor of plants and animals, but lost in land plants. We sequenced the [\~{}]120-megabase nuclear genome of Chlamydomonas and performed comparative phylogenomic analyses, identifying genes encoding uncharacterized proteins that are likely associated with the function and biogenesis of chloroplasts or eukaryotic flagella. Analyses of the Chlamydomonas genome advance our understanding of the ancestral eukaryotic cell, reveal previously unknown genes associated with photosynthetic and flagellar functions, and establish links between ciliopathy and the composition and function of flagella. 10.1126/science.1143609}, author = {Merchant, Sabeeha S. and Prochnik, Simon E. and Vallon, Olivier and Harris, Elizabeth H. and Karpowicz, Steven J. and Witman, George B. and Terry, Astrid and Salamov, Asaf and Fritz-Laylin, Lillian K. and Marechal-Drouard, Laurence and Marshall, Wallace F. and Qu, Liang-Hu and Nelson, David R. and Sanderfoot, Anton A. and Spalding, Martin H. and Kapitonov, Vladimir V. and Ren, Qinghu and Ferris, Patrick and Lindquist, Erika and Shapiro, Harris and Lucas, Susan M. and Grimwood, Jane and Schmutz, Jeremy and Cardol, Pierre and Cerutti, Heriberto and Chanfreau, Guillaume and Chen, Chun-Long and Cognat, Valerie and Croft, Martin T. and Dent, Rachel and Dutcher, Susan and Fernandez, Emilio and Fukuzawa, Hideya and Gonzalez-Ballester, David and Gonzalez-Halphen, Diego and Hallmann, Armin and Hanikenne, Marc and Hippler, Michael and Inwood, William and Jabbari, Kamel and Kalanon, Ming and Kuras, Richard and Lefebvre, Paul A. and Lemaire, Stephane D. and Lobanov, Alexey V. and Lohr, Martin and Manuell, Andrea and Meier, Iris and Mets, Laurens and Mittag, Maria and Mittelmeier, Telsa and Moroney, James V. and Moseley, Jeffrey and Napoli, Carolyn and Nedelcu, Aurora M. and Niyogi, Krishna and Novoselov, Sergey V. and Paulsen, Ian T. and Pazour, Greg and Purton, Saul and Ral, Jean-Philippe and Riano-Pachon, Diego M. and Riekhof, Wayne and Rymarquis, Linda and Schroda, Michael and Stern, David and Umen, James and Willows, Robert and Wilson, Nedra and Zimmer, Sara L. and Allmer, Jens and Balk, Janneke and Bisova, Katerina and Chen, Chong-Jian and Elias, Marek and Gendler, Karla and Hauser, Charles and Lamb, Mary R. and Ledford, Heidi and Long, Joanne C. and Minagawa, Jun and Page, M. Dudley and Pan, Junmin and Pootakham, Wirulda and Roje, Sanja and Rose, Annkatrin and Stahlberg, Eric and Terauchi, Aimee M. and Yang, Pinfen and Ball, Steven and Bowler, Chris and Dieckmann, Carol L. and Gladyshev, Vadim N. and Green, Pamela and Jorgensen, Richard and Mayfield, Stephen and Mueller-Roeber, Bernd and Rajamani, Sathish and Sayre, Richard T. and Brokstein, Peter and Dubchak, Inna and Goodstein, David and Hornick, Leila and Huang, Y. Wayne and Jhaveri, Jinal and Luo, Yigong and Martinez, Diego and Ngau, Wing C. and Otillar, Bobby and Poliakov, Alexander and Porter, Aaron and Szajkowski, Lukasz and Werner, Gregory and Zhou, Kemin and Grigoriev, Igor V. and Rokhsar, Daniel S. and Grossman, Arthur R.}, citeulike-article-id = {1767644}, citeulike-linkout-0 = {http://dx.doi.org/10.1126/science.1143609}, citeulike-linkout-1 = {http://www.sciencemag.org/content/318/5848/245.abstract}, citeulike-linkout-2 = {http://www.sciencemag.org/content/318/5848/245.full.pdf}, citeulike-linkout-3 = {http://www.sciencemag.org/cgi/content/abstract/318/5848/245}, citeulike-linkout-4 = {http://view.ncbi.nlm.nih.gov/pubmed/17932292}, citeulike-linkout-5 = {http://www.hubmed.org/display.cgi?uids=17932292}, day = {12}, doi = {10.1126/science.1143609}, issn = {1095-9203}, journal = {Science}, keywords = {genome, phylogeny, sequence}, month = {October}, number = {5848}, pages = {245--250}, posted-at = {2007-10-14 19:50:22}, priority = {2}, title = {The Chlamydomonas Genome Reveals the Evolution of Key Animal and Plant Functions}, url = {http://dx.doi.org/10.1126/science.1143609}, volume = {318}, year = {2007} }

TY - JOUR ID - citeulike:1767644 L3 - citeulike-article-id:1767644 N2 - Chlamydomonas reinhardtii is a unicellular green alga whose lineage diverged from land plants over 1 billion years ago. It is a model system for studying chloroplast-based photosynthesis, as well as the structure, assembly, and function of eukaryotic flagella (cilia), which were inherited from the common ancestor of plants and animals, but lost in land plants. We sequenced the [~]120-megabase nuclear genome of Chlamydomonas and performed comparative phylogenomic analyses, identifying genes encoding uncharacterized proteins that are likely associated with the function and biogenesis of chloroplasts or eukaryotic flagella. Analyses of the Chlamydomonas genome advance our understanding of the ancestral eukaryotic cell, reveal previously unknown genes associated with photosynthetic and flagellar functions, and establish links between ciliopathy and the composition and function of flagella. 10.1126/science.1143609 IS - 5848 JF - Science SN - 1095-9203 EP - 250 TI - The Chlamydomonas Genome Reveals the Evolution of Key Animal and Plant Functions VL - 318 SP - 245 KW - genome KW - phylogeny KW - sequence AU - Merchant, Sabeeha AU - Prochnik, Simon AU - Vallon, Olivier AU - Harris, Elizabeth AU - Karpowicz, Steven AU - Witman, George AU - Terry, Astrid AU - Salamov, Asaf AU - Fritz-Laylin, Lillian AU - Marechal-Drouard, Laurence AU - Marshall, Wallace AU - Qu, Liang-Hu AU - Nelson, David AU - Sanderfoot, Anton AU - Spalding, Martin AU - Kapitonov, Vladimir AU - Ren, Qinghu AU - Ferris, Patrick AU - Lindquist, Erika AU - Shapiro, Harris AU - Lucas, Susan AU - Grimwood, Jane AU - Schmutz, Jeremy AU - Cardol, Pierre AU - Cerutti, Heriberto AU - Chanfreau, Guillaume AU - Chen, Chun-Long AU - Cognat, Valerie AU - Croft, Martin AU - Dent, Rachel AU - Dutcher, Susan AU - Fernandez, Emilio AU - Fukuzawa, Hideya AU - Gonzalez-Ballester, David AU - Gonzalez-Halphen, Diego AU - Hallmann, Armin AU - Hanikenne, Marc AU - Hippler, Michael AU - Inwood, William AU - Jabbari, Kamel AU - Kalanon, Ming AU - Kuras, Richard AU - Lefebvre, Paul AU - Lemaire, Stephane AU - Lobanov, Alexey AU - Lohr, Martin AU - Manuell, Andrea AU - Meier, Iris AU - Mets, Laurens AU - Mittag, Maria AU - Mittelmeier, Telsa AU - Moroney, James AU - Moseley, Jeffrey AU - Napoli, Carolyn AU - Nedelcu, Aurora AU - Niyogi, Krishna AU - Novoselov, Sergey AU - Paulsen, Ian AU - Pazour, Greg AU - Purton, Saul AU - Ral, Jean-Philippe AU - Riano-Pachon, Diego AU - Riekhof, Wayne AU - Rymarquis, Linda AU - Schroda, Michael AU - Stern, David AU - Umen, James AU - Willows, Robert AU - Wilson, Nedra AU - Zimmer, Sara AU - Allmer, Jens AU - Balk, Janneke AU - Bisova, Katerina AU - Chen, Chong-Jian AU - Elias, Marek AU - Gendler, Karla AU - Hauser, Charles AU - Lamb, Mary AU - Ledford, Heidi AU - Long, Joanne AU - Minagawa, Jun AU - Page, Dudley AU - Pan, Junmin AU - Pootakham, Wirulda AU - Roje, Sanja AU - Rose, Annkatrin AU - Stahlberg, Eric AU - Terauchi, Aimee AU - Yang, Pinfen AU - Ball, Steven AU - Bowler, Chris AU - Dieckmann, Carol AU - Gladyshev, Vadim AU - Green, Pamela AU - Jorgensen, Richard AU - Mayfield, Stephen AU - Mueller-Roeber, Bernd AU - Rajamani, Sathish AU - Sayre, Richard AU - Brokstein, Peter AU - Dubchak, Inna AU - Goodstein, David AU - Hornick, Leila AU - Huang, Wayne AU - Jhaveri, Jinal AU - Luo, Yigong AU - Martinez, Diego AU - Ngau, Wing AU - Otillar, Bobby AU - Poliakov, Alexander AU - Porter, Aaron AU - Szajkowski, Lukasz AU - Werner, Gregory AU - Zhou, Kemin AU - Grigoriev, Igor AU - Rokhsar, Daniel AU - Grossman, Arthur PY - 2007/10/12/ UR - http://dx.doi.org/10.1126/science.1143609 ER -