CORUM: the comprehensive resource of mammalian protein complexes. Export

@article{Ruepp2008, abstract = {Protein complexes are key molecular entities that integrate multiple gene products to perform cellular functions. The CORUM (http://mips.gsf.de/genre/proj/corum/index.html) database is a collection of experimentally verified mammalian protein complexes. Information is manually derived by critical reading of the scientific literature from expert annotators. Information about protein complexes includes protein complex names, subunits, literature references as well as the function of the complexes. For functional annotation, we use the FunCat catalogue that enables to organize the protein complex space into biologically meaningful subsets. The database contains more than 1750 protein complexes that are built from 2400 different genes, thus representing 12\% of the protein-coding genes in human. A web-based system is available to query, view and download the data. CORUM provides a comprehensive dataset of protein complexes for discoveries in systems biology, analyses of protein networks and protein complex-associated diseases. Comparable to the MIPS reference dataset of protein complexes from yeast, CORUM intends to serve as a reference for mammalian protein complexes.}, address = {Institute for Bioinformatics (MIPS), German Research Center for Environmental Health, Ingolstaedter Landstrasse 1, D-85764 Neuherberg, Germany. andreas.ruepp@gsf.de}, author = {Ruepp, Andreas and Brauner, Barbara and Dunger-Kaltenbach, Irmtraud and Frishman, Goar and Montrone, Corinna and Stransky, Michael and Waegele, Brigitte and Schmidt, Thorsten and Doudieu, Octave Noubibou N. and St\"{u}mpflen, Volker and Mewes, H. Werner}, citeulike-article-id = {2249143}, citeulike-linkout-0 = {http://dx.doi.org/10.1093/nar/gkm936}, citeulike-linkout-1 = {http://nar.oxfordjournals.org/cgi/content/abstract/36/suppl_1/D646}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/17965090}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=17965090}, day = {11}, doi = {10.1093/nar/gkm936}, issn = {1362-4962}, journal = {Nucleic acids research}, keywords = {human\_complexes}, month = {January}, number = {Database issue}, pages = {D646--650}, posted-at = {2009-08-18 21:06:12}, priority = {2}, title = {CORUM: the comprehensive resource of mammalian protein complexes.}, url = {http://dx.doi.org/10.1093/nar/gkm936}, volume = {36}, year = {2008} }

TY - JOUR ID - Ruepp2008 L3 - citeulike-article-id:2249143 N2 - Protein complexes are key molecular entities that integrate multiple gene products to perform cellular functions. The CORUM (http://mips.gsf.de/genre/proj/corum/index.html) database is a collection of experimentally verified mammalian protein complexes. Information is manually derived by critical reading of the scientific literature from expert annotators. Information about protein complexes includes protein complex names, subunits, literature references as well as the function of the complexes. For functional annotation, we use the FunCat catalogue that enables to organize the protein complex space into biologically meaningful subsets. The database contains more than 1750 protein complexes that are built from 2400 different genes, thus representing 12% of the protein-coding genes in human. A web-based system is available to query, view and download the data. CORUM provides a comprehensive dataset of protein complexes for discoveries in systems biology, analyses of protein networks and protein complex-associated diseases. Comparable to the MIPS reference dataset of protein complexes from yeast, CORUM intends to serve as a reference for mammalian protein complexes. IS - Database issue JF - Nucleic acids research SN - 1362-4962 AD - Institute for Bioinformatics (MIPS), German Research Center for Environmental Health, Ingolstaedter Landstrasse 1, D-85764 Neuherberg, Germany. andreas.ruepp@gsf.de EP - 650 TI - CORUM: the comprehensive resource of mammalian protein complexes. VL - 36 SP - D646 KW - human_complexes AU - Ruepp, Andreas AU - Brauner, Barbara AU - Dunger-Kaltenbach, Irmtraud AU - Frishman, Goar AU - Montrone, Corinna AU - Stransky, Michael AU - Waegele, Brigitte AU - Schmidt, Thorsten AU - Doudieu, Octave Noubibou AU - Stümpflen, Volker AU - Mewes, Werner PY - 2008/01/11/ UR - http://dx.doi.org/10.1093/nar/gkm936 ER -