Altered circadian rhythms regulate growth vigour in hybrids and allopolyploids Export

@article{citeulike:3681668, abstract = {Segregating hybrids and stable allopolyploids display morphological vigour, and Arabidopsis allotetraploids are larger than the parents Arabidopsis thaliana and Arabidopsis arenosa\&\#20;the mechanisms for this are unknown. Circadian clocks mediate metabolic pathways and increase fitness in animals and plants. Here we report that epigenetic modifications of the circadian clock genes CIRCADIAN CLOCK ASSOCIATED 1 (CCA1) and LATE ELONGATED HYPOCOTYL (LHY) and their reciprocal regulators TIMING OF CAB EXPRESSION 1 (TOC1) and GIGANTEA (GI) mediate expression changes in downstream genes and pathways. During the day, epigenetic repression of CCA1 and LHY induced the expression of TOC1, GI and downstream genes containing evening elements in chlorophyll and starch metabolic pathways in allotetraploids and F1 hybrids, which produced more chlorophyll and starch than the parents in the same environment. Mutations in cca1 and cca1\&\#9;lhy and the daily repression of cca1 by RNA interference (RNAi) in TOC1::cca1(RNAi) transgenic plants increased the expression of downstream genes and increased chlorophyll and starch content, whereas constitutively expressing CCA1 or ectopically expressing TOC1::CCA1 had the opposite effect. The causal effects of CCA1 on output traits suggest that hybrids and allopolyploids gain advantages from the control of circadian-mediated physiological and metabolic pathways, leading to growth vigour and increased biomass.}, author = {Ni, Zhongfu and Kim, Eun-Deok and Ha, Misook and Lackey, Erika and Liu, Jianxin and Zhang, Yirong and Sun, Qixin and Chen, Z. Jeffrey}, citeulike-article-id = {3681668}, citeulike-linkout-0 = {http://dx.doi.org/10.1038/nature07523}, citeulike-linkout-1 = {http://dx.doi.org/10.1038/nature07523}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/19029881}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=19029881}, day = {15}, doi = {10.1038/nature07523}, issn = {0028-0836}, journal = {Nature}, keywords = {cca1, epigenetic, gi, lhy, toc1}, month = {January}, number = {7227}, pages = {327--331}, posted-at = {2009-08-10 16:53:29}, priority = {0}, publisher = {Macmillan Publishers Limited. All rights reserved}, title = {Altered circadian rhythms regulate growth vigour in hybrids and allopolyploids}, url = {http://dx.doi.org/10.1038/nature07523}, volume = {457}, year = {2009} }

TY - JOUR ID - citeulike:3681668 L3 - citeulike-article-id:3681668 N2 - Segregating hybrids and stable allopolyploids display morphological vigour, and Arabidopsis allotetraploids are larger than the parents Arabidopsis thaliana and Arabidopsis arenosathe mechanisms for this are unknown. Circadian clocks mediate metabolic pathways and increase fitness in animals and plants. Here we report that epigenetic modifications of the circadian clock genes CIRCADIAN CLOCK ASSOCIATED 1 (CCA1) and LATE ELONGATED HYPOCOTYL (LHY) and their reciprocal regulators TIMING OF CAB EXPRESSION 1 (TOC1) and GIGANTEA (GI) mediate expression changes in downstream genes and pathways. During the day, epigenetic repression of CCA1 and LHY induced the expression of TOC1, GI and downstream genes containing evening elements in chlorophyll and starch metabolic pathways in allotetraploids and F1 hybrids, which produced more chlorophyll and starch than the parents in the same environment. Mutations in cca1 and cca1	lhy and the daily repression of cca1 by RNA interference (RNAi) in TOC1::cca1(RNAi) transgenic plants increased the expression of downstream genes and increased chlorophyll and starch content, whereas constitutively expressing CCA1 or ectopically expressing TOC1::CCA1 had the opposite effect. The causal effects of CCA1 on output traits suggest that hybrids and allopolyploids gain advantages from the control of circadian-mediated physiological and metabolic pathways, leading to growth vigour and increased biomass. IS - 7227 JF - Nature SN - 0028-0836 EP - 331 TI - Altered circadian rhythms regulate growth vigour in hybrids and allopolyploids PB - Macmillan Publishers Limited. All rights reserved VL - 457 SP - 327 KW - cca1 KW - epigenetic KW - gi KW - lhy KW - toc1 AU - Ni, Zhongfu AU - Kim, Eun-Deok AU - Ha, Misook AU - Lackey, Erika AU - Liu, Jianxin AU - Zhang, Yirong AU - Sun, Qixin AU - Chen, Jeffrey PY - 2009/01/15/ UR - http://dx.doi.org/10.1038/nature07523 ER -