Use and misuse of the gene ontology annotations Export

by: Seung Yon Rhee, Valerie Wood, Kara Dolinski, Sorin Draghici

Nature Reviews Genetics, Vol. 9, No. 7. (13 May 2008), pp. 509-515.

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Abstract

The Gene Ontology (GO) project is a collaboration among model organism databases to describe gene products from all organisms using a consistent and computable language. GO produces sets of explicitly defined, structured vocabularies that describe biological processes, molecular functions and cellular components of gene products in both a computer- and human-readable manner. Here we describe key aspects of GO, which, when overlooked, can cause erroneous results, and address how these pitfalls can be avoided.

@article{citeulike:2800782, abstract = {The Gene Ontology (GO) project is a collaboration among model organism databases to describe gene products from all organisms using a consistent and computable language. GO produces sets of explicitly defined, structured vocabularies that describe biological processes, molecular functions and cellular components of gene products in both a computer- and human-readable manner. Here we describe key aspects of GO, which, when overlooked, can cause erroneous results, and address how these pitfalls can be avoided.}, address = {Carnegie Institution for Science, Department of Plant Biology, 260 Panama Street, Stanford, California 94305, USA.}, author = {Yon Rhee, Seung and Wood, Valerie and Dolinski, Kara and Draghici, Sorin}, citeulike-article-id = {2800782}, citeulike-linkout-0 = {http://dx.doi.org/10.1038/nrg2363}, citeulike-linkout-1 = {http://dx.doi.org/10.1038/nrg2363}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/18475267}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=18475267}, day = {13}, doi = {10.1038/nrg2363}, issn = {1471-0056}, journal = {Nature Reviews Genetics}, keywords = {gene\_ontology}, month = {May}, number = {7}, pages = {509--515}, posted-at = {2009-11-04 16:49:01}, priority = {2}, publisher = {Nature Publishing Group}, title = {Use and misuse of the gene ontology annotations}, url = {http://dx.doi.org/10.1038/nrg2363}, volume = {9}, year = {2008} }

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TY - JOUR ID - citeulike:2800782 L3 - citeulike-article-id:2800782 N2 - The Gene Ontology (GO) project is a collaboration among model organism databases to describe gene products from all organisms using a consistent and computable language. GO produces sets of explicitly defined, structured vocabularies that describe biological processes, molecular functions and cellular components of gene products in both a computer- and human-readable manner. Here we describe key aspects of GO, which, when overlooked, can cause erroneous results, and address how these pitfalls can be avoided. IS - 7 JF - Nature Reviews Genetics SN - 1471-0056 AD - Carnegie Institution for Science, Department of Plant Biology, 260 Panama Street, Stanford, California 94305, USA. EP - 515 TI - Use and misuse of the gene ontology annotations PB - Nature Publishing Group VL - 9 SP - 509 KW - gene_ontology AU - Yon Rhee, Seung AU - Wood, Valerie AU - Dolinski, Kara AU - Draghici, Sorin PY - 2008/05/13/ UR - http://dx.doi.org/10.1038/nrg2363 ER -

Use and misuse of the gene ontology annotations Export

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