Lowering industry firewalls: pre-competitive informatics initiatives in drug discovery Export

@article{citeulike:5719014, abstract = {Pharmaceutical research and development is facing substantial challenges that have prompted the industry to shift funding from early- to late-stage projects. Among the effects is a major change in the attitude of many companies to their internal bioinformatics resources: the focus has moved from the vigorous pursuit of intellectual property towards exploration of pre-competitive cross-industry collaborations and engagement with the public domain. High-quality, open and accessible data are the foundation of pre-competitive research, and strong public–private partnerships have considerable potential to enhance public data resources, which would benefit everyone engaged in drug discovery. In this article, we discuss the background to these changes and propose new areas of collaboration in computational biology and chemistry between the public domain and the pharmaceutical industry.}, author = {Barnes, Michael R. and Harland, Lee and Foord, Steven M. and Hall, Matthew D. and Dix, Ian and Thomas, Scott and Williams-Jones, Bryn I. and Brouwer, Cory R.}, citeulike-article-id = {5719014}, citeulike-linkout-0 = {http://dx.doi.org/10.1038/nrd2944}, citeulike-linkout-1 = {http://dx.doi.org/10.1038/nrd2944}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/19609266}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=19609266}, comment = {via http://www.genomeweb.com/informatics/tear-down-firewall-pharma-scientists-call-pre-competitive-approach-bioinformatic}, day = {17}, doi = {10.1038/nrd2944}, issn = {1474-1776}, journal = {Nature Reviews Drug Discovery}, keywords = {drug-discovery, open-access}, month = {July}, number = {9}, pages = {701--708}, posted-at = {2009-09-13 21:20:10}, priority = {2}, publisher = {Nature Publishing Group}, title = {Lowering industry firewalls: pre-competitive informatics initiatives in drug discovery}, url = {http://dx.doi.org/10.1038/nrd2944}, volume = {8}, year = {2009} }

TY - JOUR ID - citeulike:5719014 L3 - citeulike-article-id:5719014 N2 - Pharmaceutical research and development is facing substantial challenges that have prompted the industry to shift funding from early- to late-stage projects. Among the effects is a major change in the attitude of many companies to their internal bioinformatics resources: the focus has moved from the vigorous pursuit of intellectual property towards exploration of pre-competitive cross-industry collaborations and engagement with the public domain. High-quality, open and accessible data are the foundation of pre-competitive research, and strong public–private partnerships have considerable potential to enhance public data resources, which would benefit everyone engaged in drug discovery. In this article, we discuss the background to these changes and propose new areas of collaboration in computational biology and chemistry between the public domain and the pharmaceutical industry. IS - 9 JF - Nature Reviews Drug Discovery SN - 1474-1776 EP - 708 TI - Lowering industry firewalls: pre-competitive informatics initiatives in drug discovery PB - Nature Publishing Group VL - 8 SP - 701 KW - drug-discovery KW - open-access N1 - via http://www.genomeweb.com/informatics/tear-down-firewall-pharma-scientists-call-pre-competitive-approach-bioinformatic AU - Barnes, Michael AU - Harland, Lee AU - Foord, Steven AU - Hall, Matthew AU - Dix, Ian AU - Thomas, Scott AU - Williams-Jones, Bryn AU - Brouwer, Cory PY - 2009/07/17/ UR - http://dx.doi.org/10.1038/nrd2944 ER -