Beta oscillations in a large-scale sensorimotor cortical network: directional influences revealed by Granger causality. Export

@article{Brovelli2004, abstract = {Previous studies have shown that synchronized beta frequency (14-30 Hz) oscillations in the primary motor cortex are involved in maintaining steady contractions of contralateral arm and hand muscles. However, little is known about the role of postcentral cortical areas in motor maintenance and their patterns of interaction with motor cortex. We investigated the functional relations of beta-synchronized neuronal assemblies in pre- and postcentral areas of two monkeys as they pressed a hand lever during the wait period of a visual discrimination task. By using power and coherence spectral analysis, we identified a beta-synchronized large-scale network linking pre- and postcentral areas. We then used Granger causality spectra to measure directional influences among recording sites. In both monkeys, strong Granger causal influences were observed from primary somatosensory cortex to both motor cortex and inferior posterior parietal cortex, with the latter area also exerting Granger causal influences on motor cortex. Granger causal influences from motor cortex to postcentral sites, however, were weak in one monkey and not observed in the other. These results are the first, to our knowledge, to demonstrate in awake monkeys that synchronized beta oscillations bind multiple sensorimotor areas into a large-scale network during motor maintenance behavior and carry Granger causal influences from primary somatosensory and inferior posterior parietal cortices to motor cortex.}, address = {Center for Complex Systems and Brain Sciences, Florida Atlantic University, Boca Raton, FL 33431, USA.}, author = {Brovelli, Andrea and Ding, Mingzhou and Ledberg, Anders and Chen, Yonghong and Nakamura, Richard and Bressler, Steven L.}, citeulike-article-id = {500306}, citeulike-linkout-0 = {http://dx.doi.org/10.1073/pnas.0308538101}, citeulike-linkout-1 = {http://www.pnas.org/content/101/26/9849.abstract}, citeulike-linkout-2 = {http://www.pnas.org/content/101/26/9849.full.pdf}, citeulike-linkout-3 = {http://www.pnas.org/cgi/content/abstract/101/26/9849}, citeulike-linkout-4 = {http://view.ncbi.nlm.nih.gov/pubmed/15210971}, citeulike-linkout-5 = {http://www.hubmed.org/display.cgi?uids=15210971}, day = {29}, doi = {10.1073/pnas.0308538101}, issn = {0027-8424}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, keywords = {neurodynamics}, month = {June}, number = {26}, pages = {9849--9854}, posted-at = {2008-06-30 00:19:22}, priority = {2}, title = {Beta oscillations in a large-scale sensorimotor cortical network: directional influences revealed by Granger causality.}, url = {http://dx.doi.org/10.1073/pnas.0308538101}, volume = {101}, year = {2004} }

TY - JOUR ID - Brovelli2004 L3 - citeulike-article-id:500306 N2 - Previous studies have shown that synchronized beta frequency (14-30 Hz) oscillations in the primary motor cortex are involved in maintaining steady contractions of contralateral arm and hand muscles. However, little is known about the role of postcentral cortical areas in motor maintenance and their patterns of interaction with motor cortex. We investigated the functional relations of beta-synchronized neuronal assemblies in pre- and postcentral areas of two monkeys as they pressed a hand lever during the wait period of a visual discrimination task. By using power and coherence spectral analysis, we identified a beta-synchronized large-scale network linking pre- and postcentral areas. We then used Granger causality spectra to measure directional influences among recording sites. In both monkeys, strong Granger causal influences were observed from primary somatosensory cortex to both motor cortex and inferior posterior parietal cortex, with the latter area also exerting Granger causal influences on motor cortex. Granger causal influences from motor cortex to postcentral sites, however, were weak in one monkey and not observed in the other. These results are the first, to our knowledge, to demonstrate in awake monkeys that synchronized beta oscillations bind multiple sensorimotor areas into a large-scale network during motor maintenance behavior and carry Granger causal influences from primary somatosensory and inferior posterior parietal cortices to motor cortex. IS - 26 JF - Proceedings of the National Academy of Sciences of the United States of America SN - 0027-8424 AD - Center for Complex Systems and Brain Sciences, Florida Atlantic University, Boca Raton, FL 33431, USA. EP - 9854 TI - Beta oscillations in a large-scale sensorimotor cortical network: directional influences revealed by Granger causality. VL - 101 SP - 9849 KW - neurodynamics AU - Brovelli, Andrea AU - Ding, Mingzhou AU - Ledberg, Anders AU - Chen, Yonghong AU - Nakamura, Richard AU - Bressler, Steven PY - 2004/06/29/ UR - http://dx.doi.org/10.1073/pnas.0308538101 ER -