Rapid structural and epigenetic changes in polyploid and aneuploid genomes Export

@article{citeulike:2244448, abstract = {Recent work with plants has demonstrated that genome instability can be triggered by a change in chromosome number arising from either whole genome duplications (polyploidy) or loss/gain of individual chromosomes (aneuploidy). This genome instability is manifested as rapid structural and epigenetic alterations that can occur somatically or meiotically within a few generations after heteroploid formation. The intrinsic instability of newly formed polyploid and aneuploid genomes has relevance for genome evolution and human carcinogenesis, and points toward recombinational and epigenetic mechanisms that sense and respond to chromosome numerical changes. BioEssays 21:761-767, 1999. {\copyright} 1999 John Wiley \& Sons, Inc.}, address = {Institute of Molecular Biology, Austrian Academy of Sciences, Billrothstrasse 11, A-5020 Salzburg, Austria.; Friedrich-Miescher-Institute, P.O. Box 2543, CH-4002 Basel, Switzerland.}, author = {Matzke, M. A. and Scheid, Mittelsten O. and Matzke, A. J. M.}, citeulike-article-id = {2244448}, citeulike-linkout-0 = {http://dx.doi.org/10.1002/(SICI)1521-1878(199909)21:9%3C761::AID-BIES7%3E3.0.CO;2-C}, citeulike-linkout-1 = {http://www3.interscience.wiley.com/cgi-bin/abstract/63500165/ABSTRACT}, doi = {10.1002/(SICI)1521-1878(199909)21:9%3C761::AID-BIES7%3E3.0.CO;2-C}, journal = {BioEssays}, keywords = {epigenetics, methylation, polyploidy}, number = {9}, pages = {761--767}, posted-at = {2008-01-17 11:18:45}, priority = {2}, title = {Rapid structural and epigenetic changes in polyploid and aneuploid genomes}, url = {http://dx.doi.org/10.1002/(SICI)1521-1878(199909)21:9%3C761::AID-BIES7%3E3.0.CO;2-C}, volume = {21}, year = {1999} }

TY - JOUR ID - citeulike:2244448 L3 - citeulike-article-id:2244448 N2 - Recent work with plants has demonstrated that genome instability can be triggered by a change in chromosome number arising from either whole genome duplications (polyploidy) or loss/gain of individual chromosomes (aneuploidy). This genome instability is manifested as rapid structural and epigenetic alterations that can occur somatically or meiotically within a few generations after heteroploid formation. The intrinsic instability of newly formed polyploid and aneuploid genomes has relevance for genome evolution and human carcinogenesis, and points toward recombinational and epigenetic mechanisms that sense and respond to chromosome numerical changes. BioEssays 21:761-767, 1999. © 1999 John Wiley & Sons, Inc. IS - 9 JF - BioEssays AD - Institute of Molecular Biology, Austrian Academy of Sciences, Billrothstrasse 11, A-5020 Salzburg, Austria.; Friedrich-Miescher-Institute, P.O. Box 2543, CH-4002 Basel, Switzerland. EP - 767 TI - Rapid structural and epigenetic changes in polyploid and aneuploid genomes VL - 21 SP - 761 KW - epigenetics KW - methylation KW - polyploidy AU - Matzke, MA AU - Scheid, Mittelsten AU - Matzke, AJM PY - 1999/// UR - http://dx.doi.org/10.1002/(SICI)1521-1878(199909)21:9%3C761::AID-BIES7%3E3.0.CO;2-C ER -