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Journal of Clinical Endocrinology & Metabolism, Vol. 57, No. 3. (01 September 1983), pp. 592-596, doi:10.1210/jcem-57-3-592 Key: citeulike:11861436
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To determine the effect of (β-endorphin on the pituitary-adrenal axis, human synthetic β-endorphin was infused iv in 10 normal human subjects. Either β-endorphin (0.3, 1.0, and 3.0 μg/kg·min, each dose for 30 min) or a control (sham) infusion of 5% dextrose water was administered in a blind fashion in the same subjects on 2 successive days. Plasma ACTH and cortisol and serum human GH and PRL levels were measured 30 min before and then every 30 min for 210 min during and after both the β-endorphin and control infusions.
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