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Endocrine Consequences of Long-Term Intrathecal Administration of Opioids

by: Roger Abs, Johan Verhelst, Jan Maeyaert, Jean-Pierre Van Buyten, Frank Opsomer, Hugo Adriaensen, Jan Verlooy, Tony Van Havenbergh, Mike Smet, Kristien Van Acker
Journal of Clinical Endocrinology & Metabolism, Vol. 85, No. 6. (01 June 2000), pp. 2215-2222, doi:10.1210/jc.85.6.2215  Key: citeulike:11861439

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Abstract

Intrathecal administration of opioids is a very efficient tool in the long-term control of intractable nonmalignant pain. However, despite the well known role of opioids in endocrine regulation, few data are available about possible effects on hypothalamic-pituitary function during this treatment.


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