CFinder: locating cliques and overlapping modules in biological networks Export

@article{citeulike:579612, abstract = {Summary: Most cellular tasks are performed not by individual proteins, but by groups of functionally associated proteins, often referred to as modules. In a protein assocation network modules appear as groups of densely interconnected nodes, also called communities or clusters. These modules often overlap with each other and form a network of their own, in which nodes (links) represent the modules (overlaps). We introduce CFinder, a fast program locating and visualizing overlapping, densely interconnected groups of nodes in undirected graphs, and allowing the user to easily navigate between the original graph and the web of these groups. We show that in gene (protein) association networks CFinder can be used to predict the function(s) of a single protein and to discover novel modules. CFinder is also very efficient for locating the cliques of large sparse graphs. Availability: CFinder (for Windows, Linux and Macintosh) and its manual can be downloaded from http://angel.elte.hu/clustering.}, author = {Adamcsek, Balazs and Palla, Gergely and Farkas, Illes J. and Derenyi, Imre and Vicsek, Tamas}, citeulike-article-id = {579612}, citeulike-linkout-0 = {http://dx.doi.org/10.1093/bioinformatics/btl039}, citeulike-linkout-1 = {http://bioinformatics.oxfordjournals.org/content/22/8/1021.abstract}, citeulike-linkout-2 = {http://bioinformatics.oxfordjournals.org/content/22/8/1021.full.pdf}, citeulike-linkout-3 = {http://bioinformatics.oxfordjournals.org/cgi/content/abstract/22/8/1021}, citeulike-linkout-4 = {http://www.ingentaconnect.com/content/oup/cabios/2006/00000022/00000008/art01021}, citeulike-linkout-5 = {http://view.ncbi.nlm.nih.gov/pubmed/16473872}, citeulike-linkout-6 = {http://www.hubmed.org/display.cgi?uids=16473872}, day = {15}, doi = {10.1093/bioinformatics/btl039}, issn = {1367-4803}, journal = {Bioinformatics}, keywords = {modularity, overlapping, probmod}, month = {April}, number = {8}, pages = {1021--1023}, posted-at = {2008-06-18 22:31:57}, priority = {2}, publisher = {Oxford University Press}, title = {CFinder: locating cliques and overlapping modules in biological networks}, url = {http://dx.doi.org/10.1093/bioinformatics/btl039}, volume = {22}, year = {2006} }

TY - JOUR ID - citeulike:579612 L3 - citeulike-article-id:579612 N2 - Summary: Most cellular tasks are performed not by individual proteins, but by groups of functionally associated proteins, often referred to as modules. In a protein assocation network modules appear as groups of densely interconnected nodes, also called communities or clusters. These modules often overlap with each other and form a network of their own, in which nodes (links) represent the modules (overlaps). We introduce CFinder, a fast program locating and visualizing overlapping, densely interconnected groups of nodes in undirected graphs, and allowing the user to easily navigate between the original graph and the web of these groups. We show that in gene (protein) association networks CFinder can be used to predict the function(s) of a single protein and to discover novel modules. CFinder is also very efficient for locating the cliques of large sparse graphs. Availability: CFinder (for Windows, Linux and Macintosh) and its manual can be downloaded from http://angel.elte.hu/clustering. IS - 8 JF - Bioinformatics SN - 1367-4803 EP - 1023 TI - CFinder: locating cliques and overlapping modules in biological networks PB - Oxford University Press VL - 22 SP - 1021 KW - modularity KW - overlapping KW - probmod AU - Adamcsek, Balazs AU - Palla, Gergely AU - Farkas, Illes AU - Derenyi, Imre AU - Vicsek, Tamas PY - 2006/04/15/ UR - http://dx.doi.org/10.1093/bioinformatics/btl039 ER -