emiko's library 170 articles Export

	THE HEPATITIS C VIRUS CORE PROTEIN CONTAINS A BH3 DOMAIN THAT REGULATES APOPTOSIS THROUGH SPECIFIC INTERACTION WITH HUMAN MCL-1 [My Copy] J. Virol. (15 July 2009), JVI.00509-09. by Nur K. Mohd-Ismail, Lin Deng, Sunil K. Sukumaran, Victor C. Yu, Hak Hotta, Yee-Joo Tan posted to aug09lit mcl-1_interaction viral by emiko on 2009-08-05 19:28:48 as
	Apoptosis of B-cell chronic lymphocytic leukemia cells induced by a novel BH3 peptidomimetic. [My Copy] Cancer biology & therapy, Vol. 8, No. 3. (17 March 2009) by Fabio Ghiotto, Franco Fais, Claudya Tenca, et al.Valeria Tomati, Fortunato Morabito, Salvatore Casciaro, Anna Mumot, Gabriele Zoppoli, Ermanno Ciccone, Silvio Parodi, Silvia Bruno posted to aug09lit bh3_mimetic by emiko on 2009-08-03 21:48:47 as
	Alterations in the Noxa/Mcl-1 axis determine sensitivity of small cell lung cancer to the BH3 mimetic ABT-737. [My Copy] Molecular cancer therapeutics, Vol. 8, No. 4. (April 2009), pp. 883-892. by Paula Hauck, Bo H. Chao, Julie Litz, Geoffrey W. Krystal posted to abt-737 aug09lit mcl-1 by emiko on 2009-08-03 21:47:40 as
	Bax activation by the BH3-only protein Puma promotes cell dependence on antiapoptotic Bcl-2 family members. [My Copy] The Journal of cell biology, Vol. 185, No. 2. (20 April 2009), pp. 279-290. by Tristan Gallenne, Fabien Gautier, Lisa Oliver, et al.Eric Hervouet, Belinda Noël, John A. Hickman, Olivier Geneste, Pierre-François F. Cartron, François M. Vallette, Stephen Manon, Philippe Juin posted to aug09lit baxbak_activation by emiko on 2009-07-31 21:25:30 as along with 1 person paulschlesinger
	Apogossypol derivatives as pan-active inhibitors of antiapoptotic B-cell lymphoma/leukemia-2 (Bcl-2) family proteins. [My Copy] Journal of medicinal chemistry, Vol. 52, No. 14. (23 July 2009), pp. 4511-4523. by Jun Wei, Shinichi Kitada, Michele F. Rega, et al.John L. Stebbins, Dayong Zhai, Jason Cellitti, Hongbin Yuan, Aras Emdadi, Russell Dahl, Ziming Zhang, Li Yang, John C. Reed, Maurizio Pellecchia posted to aug09lit bh3_mimetic by emiko on 2009-07-31 21:24:29 as along with 1 person higueruelo
	The BH3 mimetic compound, ABT-737, synergizes with a range of cytotoxic chemotherapy agents in chronic lymphocytic leukemia. [My Copy] Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K (30 July 2009) by K. D. Mason, S. L. Khaw, K. C. Rayeroux, et al.E. Chew, E. F. Lee, W. D. Fairlie, A. P. Grigg, J. F. Seymour, J. Szer, D. C. Huang, A. W. Roberts posted to abt-737 aug09lit by emiko on 2009-07-31 21:18:38 as
	Bax activation by Bim? [My Copy] Cell death and differentiation (26 June 2009) by P. E. Czabotar, P. M. Colman, D. C. Huang posted to aug09lit baxbak_activation review by emiko on 2009-07-27 21:21:00 as along with 1 person paulschlesinger
	The automation of science. [My Copy] Science (New York, N.Y.), Vol. 324, No. 5923. (3 April 2009), pp. 85-89. by Ross D. King, Jem Rowland, Stephen G. Oliver, et al.Michael Young, Wayne Aubrey, Emma Byrne, Maria Liakata, Magdalena Markham, Pinar Pir, Larisa N. Soldatova, Andrew Sparkes, Kenneth E. Whelan, Amanda Clare posted to no-tag by emiko on 2009-04-20 01:16:16 as along with 56 people and 2 groups singhsh Sergey_gerbek schwartzjmc yyfwuhan antonkratz CulCog ckai1 jcaddy thegoose tommcdonagh tonamswish qwermish axeltan ocs TobiasAbenius CameronNeylon guhjy davidcsterratt bcondon Scis0000002 kevinemamy TRHvidsten Zephyrus arne muraken vagoskar katiehumphry Effie robertknight acrmartins psique dbikard tyrell_turing Tomste renatomilani subhacom druvus ramanuja sen_cheng coela VGreiff hagechouchin443 Benja austin stober rdiaz Fortran napvasconcelos mikel_egana allysonlister dullhunk fgibson pkonings JeremyZucker jbhiatt tmmurali NaCTeM MetabolicModeling
	How to write consistently boring scientific literature [My Copy] Oikos, Vol. 116, No. 5. (May 2007), pp. 723-727. by Kaj Sand-Jensen posted to no-tag by emiko on 2009-04-20 01:11:24 as along with 39 people and 4 groups phloflo alexknight norris lucap1949 scientificsteve saschurabi Lucap mordiano Boxus jirak vigneshjvn mxro mezhaka leocmcheung snakehsu m_lew fghjorth guhjy alm chanakam2000 micrix benoitvalley TimRooney alexhakkinen maren thegoose reconnie sobolevnrm hiranzani ahuesler MickeySchafer xtizon leonardo merj badger_master katiehumphry harrykipper iwagner mbolding Norris1 microextraction in chromatography Information Integration Architecture LABSS
	Structure of the CED-4–CED-9 complex provides insights into programmed cell death in Caenorhabditis elegans [My Copy] Nature, Vol. 437, No. 7060., pp. 831-837. by Nieng Yan, Jijie Chai, Eui S. Lee, et al.Lichuan Gu, Qun Liu, Jiaqing He, Jia-Wei Wu, David Kokel, Huilin Li, Quan Hao, Ding Xue, Yigong Shi posted to structure by emiko on 2009-04-19 03:25:06 as
	Hydrophile scanning as a complement to alanine scanning for exploring and manipulating protein-protein recognition: Application to the Bim BH3 domain [My Copy] Protein Sci (8 May 2008), ps.032896.107. by Melissa D. Boersma, Jack D. Sadowsky, York A. Tomita, Samuel H. Gellman posted to bh3_specificity by emiko on 2009-04-17 16:40:00 as along with 2 people wilbur paulschlesinger
	Bim, Bad and Bmf: intrinsically unstructured BH3-only proteins that undergo a localized conformational change upon binding to prosurvival Bcl-2 targets [My Copy] Cell Death and Differentiation, Vol. aop, No. current. by M. G. Hinds, C. Smits, R. Fredericks-Short, et al.J. M. Risk, M. Bailey, D. C. S. Huang, C. L. Day posted to bh3-only structure by emiko on 2009-04-16 20:50:28 as
	Solution structure of the proapoptotic molecule BID: a structural basis for apoptotic agonists and antagonists. [My Copy] Cell, Vol. 96, No. 5. (5 March 1999), pp. 625-634. by J. M. McDonnell, D. Fushman, C. L. Milliman, S. J. Korsmeyer, D. Cowburn posted to bh3-only structure by emiko on 2009-04-16 20:49:56 as
	Solution structure of BID, an intracellular amplifier of apoptotic signaling. [My Copy] Cell, Vol. 96, No. 5. (5 March 1999), pp. 615-624. by J. J. Chou, H. Li, G. S. Salvesen, J. Yuan, G. Wagner posted to bh3-only structure by emiko on 2009-04-16 20:49:27 as along with 1 person sjelsaes
	Structure of Bax: coregulation of dimer formation and intracellular localization. [My Copy] Cell, Vol. 103, No. 4. (10 November 2000), pp. 645-654. by M. Suzuki, R. J. Youle, N. Tjandra posted to structure by emiko on 2009-04-16 20:48:02 as
	The X-ray structure of a BAK homodimer reveals an inhibitory zinc binding site. [My Copy] Molecular cell, Vol. 24, No. 5. (8 December 2006), pp. 677-688. by T. Moldoveanu, Q. Liu, A. Tocilj, M. Watson, G. Shore, K. Gehring posted to structure by emiko on 2009-04-16 20:43:03 as
	BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax. [My Copy] Nature, Vol. 369, No. 6478. (26 May 1994), pp. 321-323. by X. M. Yin, Z. N. Oltvai, S. J. Korsmeyer posted to discovery by emiko on 2009-04-16 05:41:24 as
	Comparison of chemical inhibitors of antiapoptotic Bcl-2-family proteins [My Copy] Cell Death and Differentiation, Vol. aop, No. current. by D. Zhai, C. Jin, A. C. Satterthwait, J. C. Reed posted to bh3_mimetic by emiko on 2009-04-16 04:44:29 as along with 1 person kabookie
	A structure of the human apoptosome at 12.8 A resolution provides insights into this cell death platform. [My Copy] Structure (London, England : 1993), Vol. 13, No. 11. (November 2005), pp. 1725-1735. by X. Yu, D. Acehan, J. F. Ménétret, et al.C. R. Booth, S. J. Ludtke, S. J. Riedl, Y. Shi, X. Wang, C. W. Akey posted to structure by emiko on 2009-04-16 02:04:26 as
	Mechanical aspects of apoptosome assembly. [My Copy] Current opinion in cell biology, Vol. 18, No. 6. (December 2006), pp. 677-684. by Y. Shi posted to review by emiko on 2009-04-16 02:03:51 as
	BH3 domains define selective inhibitory interactions with BHRF-1 and KSHV BCL-2 [My Copy] Cell Death and Differentiation, Vol. aop, No. current. by A. M. Flanagan, A. Letai posted to viral by emiko on 2009-04-15 21:46:38 as
	A decade of caspases [My Copy] Oncogene, Vol. 22, No. 53. (0000), pp. 8543-8567. by Alexei Degterev, Michael Boyce, Junying Yuan posted to review by emiko on 2009-04-15 16:11:53 as
	The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1B-converting enzyme. [My Copy] Cell, Vol. 75 (1993), pp. 641-652. by J. Y. Yuan, S. Shaham, S. Ledoux, H. M. Ellis, H. R. Horvitz posted to discovery by emiko on 2009-04-15 16:08:29 as along with 2 people and 1 group thegoose2 tharris C. elegans / WormBase
	Quantitative Analysis of Pathways Controlling Extrinsic Apoptosis in Single Cells [My Copy] Molecular Cell, Vol. 30, No. 1. (11 April 2008), pp. 11-25. by John G. Albeck, John M. Burke, Bree B. Aldridge, Mingsheng Zhang, Douglas A. Lauffenburger, Peter K. Sorger posted to model by emiko on 2009-04-15 15:15:26 as along with 3 people and 1 group jaycopeland burkey brianb SorgerLab
	Modeling a snap-action, variable-delay switch controlling extrinsic cell death. [My Copy] PLoS biology, Vol. 6, No. 12. (2 December 2008), pp. 2831-2852. by J. G. Albeck, J. M. Burke, S. L. Spencer, D. A. Lauffenburger, P. K. Sorger posted to model by emiko on 2009-04-15 15:14:40 as along with 1 person cannin
	The Bcl-2 family: roles in cell survival and oncogenesis. [My Copy] Oncogene, Vol. 22, No. 53. (24 November 2003), pp. 8590-8607. by S. Cory, D. C. Huang, J. M. Adams posted to review by emiko on 2009-04-15 14:56:17 as
	The Bcl2 family: regulators of the cellular life-or-death switch. [My Copy] Nat Rev Cancer, Vol. 2, No. 9. (September 2002), pp. 647-656. by S. Cory, J. M. Adams posted to review by emiko on 2009-04-15 14:55:39 as along with 2 people sjelsaes laurabailey
	The Bcl-2 protein family: sensors and checkpoints for life-or-death decisions. [My Copy] Molecular immunology, Vol. 39, No. 11. (January 2003), pp. 615-647. by C. Borner posted to review by emiko on 2009-04-15 14:54:49 as
	Posttranslational N-Myristoylation of BID as a Molecular Switch for Targeting Mitochondria and Apoptosis [My Copy] Science, Vol. 290, No. 5497. (1 December 2000), pp. 1761-1765. by Jiping Zha, Solly Weiler, Kyoung J. Oh, Michael C. Wei, Stanley J. Korsmeyer posted to bh3-only bh3_regulation by emiko on 2009-04-15 03:43:26 as
	Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. [My Copy] Cell, Vol. 94, No. 4. (21 August 1998), pp. 481-490. by X. Luo, I. Budihardjo, H. Zou, C. Slaughter, X. Wang posted to bh3-only bh3_regulation by emiko on 2009-04-15 03:37:25 as
	Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. [My Copy] Cell, Vol. 94, No. 4. (21 August 1998), pp. 491-501. by H. Li, H. Zhu, C. J. Xu, J. Yuan posted to bh3-only bh3_regulation by emiko on 2009-04-15 03:37:11 as along with 2 people ea burkey
	Phosphorylation of bid by casein kinases I and II regulates its cleavage by caspase 8. [My Copy] Molecular cell, Vol. 8, No. 3. (September 2001), pp. 601-611. by S. Desagher, A. Osen-Sand, S. Montessuit, et al.E. Magnenat, F. Vilbois, A. Hochmann, L. Journot, B. Antonsson, J. C. Martinou posted to bh3-only bh3_regulation by emiko on 2009-04-15 03:35:39 as
	The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex. [My Copy] Molecular cell, Vol. 3, No. 3. (March 1999), pp. 287-296. by H. Puthalakath, D. C. Huang, L. A. O'Reilly, S. M. King, A. Strasser posted to bh3-only bh3_regulation by emiko on 2009-04-15 03:29:21 as along with 2 people catcremona lyrial
	Bcl-2 family members: intracellular targeting, membrane-insertion, and changes in subcellular localization [My Copy] Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, Vol. 1644, No. 2-3. (March 2004), pp. 95-105. by A. Schinzel, T. Kaufmann, C. Borner posted to review by emiko on 2009-04-15 03:22:38 as
	Cellular distribution of Bcl-2 family proteins. [My Copy] Science's STKE : signal transduction knowledge environment, Vol. 2003, No. 173. (11 March 2003) by M. Germain, G. C. Shore posted to review by emiko on 2009-04-15 03:21:44 as
	Protein phosphatase type 2C dephosphorylates BAD. [My Copy] Neurochemistry international, Vol. 42, No. 7. (June 2003), pp. 555-560. by S. Klumpp, D. Selke, J. Krieglstein posted to bh3-only bh3_regulation by emiko on 2009-04-15 03:13:45 as
	Interleukin-3-Induced Phosphorylation of BAD Through the Protein Kinase Akt [My Copy] Science, Vol. 278, No. 5338. (24 October 1997), pp. 687-689. by Luis Peso, Maribel Gonzalez-Garcia, Carmen Page, Roman Herrera, Gabriel Nunez posted to bh3-only bh3_regulation by emiko on 2009-04-15 03:09:07 as
	Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery [My Copy] Cell, Vol. 91, No. 2. (October 1997), pp. 231-241. by S. Datta, H. Dudek, X. Tao, et al.S. Masters, H. Fu, Y. Gotoh, M. E. Greenberg posted to bh3-only bh3_regulation by emiko on 2009-04-15 03:05:52 as along with 1 person bloomekj
	Acylpyrogallols as Inhibitors of Antiapoptotic Bcl-2 Proteins [My Copy] J. Med. Chem. (1 February 2008) by Guozhi Tang, Zaneta Nikolovska-Coleska, Su Qiu, Chao-Yie Yang, Jie Guo, Shaomeng Wang posted to bh3_mimetic by emiko on 2009-04-14 21:26:57 as along with 1 person higueruelo
	Targeting Bcl-2 family members with the BH3 mimetic AT-101 markedly enhances the therapeutic effects of chemotherapeutic agents in in vitro and in vivo models of B-cell lymphoma. [My Copy] Blood, Vol. 111, No. 11. (1 June 2008), pp. 5350-5358. by L. Paoluzzi, M. Gonen, J. R. Gardner, et al.J. Mastrella, D. Yang, J. Holmlund, M. Sorensen, L. Leopold, K. Manova, G. Marcucci, M. L. Heaney, O. A. O'Connor posted to bh3_mimetic by emiko on 2009-04-14 21:12:07 as
	Different pathways of cell killing by gossypol enantiomers. [My Copy] Experimental biology and medicine (Maywood, N.J.), Vol. 227, No. 6. (June 2002), pp. 398-401. by J. Qiu, L. R. Levin, J. Buck, M. M. Reidenberg posted to bh3_mimetic by emiko on 2009-04-14 21:07:04 as
	Apoptosis in Drosophila: neither fish nor fowl (nor man, nor worm). [My Copy] Journal of cell science, Vol. 118, No. Pt 9. (1 May 2005), pp. 1779-1787. by S. Kornbluth, K. White posted to review by emiko on 2009-04-14 19:38:12 as
	Genetics of programmed cell death in C. elegans: Past, present and future. [My Copy] Trends in Genetics, Vol. 14 (1998), pp. 410-416. by M. M. Metzstein, G. M. Stanfield, H. R. Horvitz posted to review by emiko on 2009-04-14 19:25:13 as along with 2 people and 1 group thegoose2 tharris C. elegans / WormBase
	Kaposi's sarcoma-associated herpesvirus encodes a functional bcl-2 homologue. [My Copy] Nature medicine, Vol. 3, No. 3. (March 1997), pp. 293-298. by R. Sarid, T. Sato, R. A. Bohenzky, J. J. Russo, Y. Chang posted to viral by emiko on 2009-04-06 23:38:59 as
	Identification of Chelerythrine as an Inhibitor of BclXL Function [My Copy] J. Biol. Chem., Vol. 278, No. 23. (30 May 2003), pp. 20453-20456. by Shing-Leng Chan, Mei C. Lee, Kuan O. Tan, et al.Lay-Kien Yang, Alex S. Lee, Horst Flotow, Nai Y. Fu, Mark S. Butler, Doel D. Soejarto, Antony D. Buss, Victor C. Yu posted to bh3_mimetic by emiko on 2009-04-02 20:50:44 as
	Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3. [My Copy] Nature cell biology, Vol. 3, No. 2. (February 2001), pp. 183-191. by S. P. Tzung, K. M. Kim, G. Basañez, et al.C. D. Giedt, J. Simon, J. Zimmerberg, K. Y. Zhang, D. M. Hockenbery posted to bh3_mimetic by emiko on 2009-04-02 20:41:30 as
	Discovery of small-molecule inhibitors of Bcl-2 through structure-based computer screening. [My Copy] Journal of medicinal chemistry, Vol. 44, No. 25. (6 December 2001), pp. 4313-4324. by I. J. Enyedy, Y. Ling, K. Nacro, et al.Y. Tomita, X. Wu, Y. Cao, R. Guo, B. Li, X. Zhu, Y. Huang, Y. Q. Long, P. P. Roller, D. Yang, S. Wang posted to bh3_mimetic by emiko on 2009-04-02 20:40:47 as
	Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells [My Copy] PNAS, Vol. 97, No. 13. (20 June 2000), pp. 7124-7129. by Jia-Lun Wang, Dongxiang Liu, Zhi-Jia Zhang, et al.Simei Shan, Xiaobing Han, Srinivasa M. Srinivasula, Carlo M. Croce, Emad S. Alnemri, Ziwei Huang posted to bh3_mimetic by emiko on 2009-04-02 20:15:02 as along with 2 people and 2 groups sangeetha higueruelo Bioinformatics insilicodrug
	Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL. [My Copy] Nat Cell Biol, Vol. 3, No. 2. (February 2001), pp. 173-182. by A. Degterev, A. Lugovskoy, M. Cardone, et al.B. Mulley, G. Wagner, T. Mitchison, J. Yuan posted to bcl-xl bh3_mimetic by emiko on 2009-04-02 20:11:34 as along with 1 person higueruelo
	Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint-cluster region near a transcriptionally active locus on chromosome 18. [My Copy] Proceedings of the National Academy of Sciences of the United States of America, Vol. 82, No. 21. (November 1985), pp. 7439-7443. by M. L. Cleary, J. Sklar posted to bcl-2 discovery by emiko on 2009-04-02 16:16:16 as

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bh3_mimetic	35
structure	35
discovery	32
bcl-2	29
bh3-only	27
mcl-1	23
review	20
bcl-xl	19
viral	15
abt-737	9
aug09lit	9
baxbak_activation	9
bh3_regulation	9
baxbak	7
expression	5
bcl-w	4
mcl-1_interaction	4
a1	3
bcl-b	3
bh3_specificity	3
method	3
model	2
stapled_bh3	2
necrosis	1

emiko's library 170 articles Export

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