Intraspecific Polymorphism to Interspecific Divergence: Genetics of Pigmentation in Drosophila Export

@article{citeulike:5998118, abstract = {Genetic changes contributing to phenotypic differences within or between species have been identified for a handful of traits, but the relationship between alleles underlying intraspecific polymorphism and interspecific divergence is largely unknown. We found that noncoding changes in the tan gene, as well as changes linked to the ebony gene, contribute to pigmentation divergence between closely related Drosophila species. Moreover, we found that alleles linked to tan and ebony fixed in one Drosophila species also contribute to variation within another species, and that multiple genotypes underlie similar phenotypes even within the same population. These alleles appear to predate speciation, which suggests that standing genetic variation present in the common ancestor gave rise to both intraspecific polymorphism and interspecific divergence. 10.1126/science.1176980}, author = {Wittkopp, Patricia J. and Stewart, Emma E. and Arnold, Lisa L. and Neidert, Adam H. and Haerum, Belinda K. and Thompson, Elizabeth M. and Akhras, Saleh and Smith-Winberry, Gabriel and Shefner, Laura}, citeulike-article-id = {5998118}, citeulike-linkout-0 = {http://dx.doi.org/10.1126/science.1176980}, citeulike-linkout-1 = {http://www.sciencemag.org/content/326/5952/540.abstract}, citeulike-linkout-2 = {http://www.sciencemag.org/content/326/5952/540.full.pdf}, citeulike-linkout-3 = {http://view.ncbi.nlm.nih.gov/pubmed/19900891}, citeulike-linkout-4 = {http://www.hubmed.org/display.cgi?uids=19900891}, day = {23}, doi = {10.1126/science.1176980}, journal = {Science}, keywords = {drosophila, phenotypic\_evolution, pigmentation, species\_divergence}, month = {October}, number = {5952}, pages = {540--544}, posted-at = {2009-11-01 02:02:43}, priority = {2}, title = {Intraspecific Polymorphism to Interspecific Divergence: Genetics of Pigmentation in Drosophila}, url = {http://dx.doi.org/10.1126/science.1176980}, volume = {326}, year = {2009} }

TY - JOUR ID - citeulike:5998118 L3 - citeulike-article-id:5998118 N2 - Genetic changes contributing to phenotypic differences within or between species have been identified for a handful of traits, but the relationship between alleles underlying intraspecific polymorphism and interspecific divergence is largely unknown. We found that noncoding changes in the tan gene, as well as changes linked to the ebony gene, contribute to pigmentation divergence between closely related Drosophila species. Moreover, we found that alleles linked to tan and ebony fixed in one Drosophila species also contribute to variation within another species, and that multiple genotypes underlie similar phenotypes even within the same population. These alleles appear to predate speciation, which suggests that standing genetic variation present in the common ancestor gave rise to both intraspecific polymorphism and interspecific divergence. 10.1126/science.1176980 IS - 5952 JF - Science EP - 544 TI - Intraspecific Polymorphism to Interspecific Divergence: Genetics of Pigmentation in Drosophila VL - 326 SP - 540 KW - drosophila KW - phenotypic_evolution KW - pigmentation KW - species_divergence AU - Wittkopp, Patricia AU - Stewart, Emma AU - Arnold, Lisa AU - Neidert, Adam AU - Haerum, Belinda AU - Thompson, Elizabeth AU - Akhras, Saleh AU - Smith-Winberry, Gabriel AU - Shefner, Laura PY - 2009/10/23/ UR - http://dx.doi.org/10.1126/science.1176980 ER -