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Translational control of localized mRNAs: restricting protein synthesis in space and time Export

Nature Reviews Molecular Cell Biology, Vol. 9, No. 12., pp. 971-980.

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As highlighted by recent genome-wide analyses in diverse organisms and cell types, subcellular targeting of mRNAs has emerged as a major mechanism for cells to establish functionally distinct compartments and structures. For protein synthesis to be spatially restricted, translation of localizing mRNAs is silenced during


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