Large histone H3 lysine 9 dimethylated chromatin blocks distinguish differentiated from embryonic stem cells Export

@article{citeulike:3923839, abstract = {Higher eukaryotes must adapt a totipotent genome to specialized cell types with stable but limited functions. One potential mechanism for lineage restriction is changes in chromatin, and differentiation-related chromatin changes have been observed for individual genes.}, author = {Wen, Bo and Wu, Hao and Shinkai, Yoichi and Irizarry, Rafael A. and Feinberg, Andrew P.}, citeulike-article-id = {3923839}, citeulike-linkout-0 = {http://dx.doi.org/10.1038/ng.297}, citeulike-linkout-1 = {http://dx.doi.org/10.1038/ng.297}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/19151716}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=19151716}, day = {18}, doi = {10.1038/ng.297}, issn = {1061-4036}, journal = {Nature Genetics}, keywords = {cancer, cell\_differentiation, histone\_methylation, stem\_cells}, month = {January}, number = {2}, pages = {246--250}, posted-at = {2009-02-08 15:47:25}, priority = {2}, publisher = {Nature Publishing Group}, title = {Large histone H3 lysine 9 dimethylated chromatin blocks distinguish differentiated from embryonic stem cells}, url = {http://dx.doi.org/10.1038/ng.297}, volume = {41}, year = {2009} }

TY - JOUR ID - citeulike:3923839 L3 - citeulike-article-id:3923839 N2 - Higher eukaryotes must adapt a totipotent genome to specialized cell types with stable but limited functions. One potential mechanism for lineage restriction is changes in chromatin, and differentiation-related chromatin changes have been observed for individual genes. IS - 2 JF - Nature Genetics SN - 1061-4036 EP - 250 TI - Large histone H3 lysine 9 dimethylated chromatin blocks distinguish differentiated from embryonic stem cells PB - Nature Publishing Group VL - 41 SP - 246 KW - cancer KW - cell_differentiation KW - histone_methylation KW - stem_cells AU - Wen, Bo AU - Wu, Hao AU - Shinkai, Yoichi AU - Irizarry, Rafael AU - Feinberg, Andrew PY - 2009/01/18/ UR - http://dx.doi.org/10.1038/ng.297 ER -