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FunNet: an integrative tool for exploring transcriptional interactions. Export

Bioinformatics (Oxford, England) (17 September 2008)

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SUMMARY: We describe here an exploratory tool, called FunNet, which implements an original systems biology approach, aiming to improve the biological relevance of the modular interaction patterns identified in transcriptional co-expression networks. A suitable analytical model, involving two abstraction layers, has been devised to relate expression profiles to the knowledge on transcripts' biological roles, extracted from genomic databases, into a comprehensive exploratory framework. This approach has been implemented into a user-friendly web tool to promote its open use by the community. AVAILABILITY: http://www.funnet.info CONTACT: edi.prifti@crc.jussieu.fr.


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