Cyclooxygenase-2 expression in the hippocampus of genetically epilepsy susceptible El mice was increased after seizure. Export

@article{citeulike:5916315, abstract = {It has been suggested that cyclooxygenase (COX)-2 and prostaglandin play a role in epilepsy. We studied the expression of COX-2 in the hippocampus and the effect of oral administration of indomethacin, a COX inhibitor, on seizure activity in genetically seizure-susceptible El mice. COX-2 protein significantly increased in the hippocampi of El mice after epileptic seizure. Indomethacin did shorten the duration from seizure onset to full recovery in El mice although the threshold and the duration of seizure were not changed.}, author = {Okada, K. and Yuhi, T. and Tsuji, S. and Yamashita, U.}, citeulike-article-id = {5916315}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/11251211}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=11251211}, day = {16}, issn = {0006-8993}, journal = {Brain research}, keywords = {cyclooxygenase, cyclooxygenase-2, el, epilepsy, hippocampus, mice, seizure, susceptible}, month = {March}, number = {2}, pages = {332--335}, posted-at = {2009-10-09 15:16:17}, priority = {2}, title = {Cyclooxygenase-2 expression in the hippocampus of genetically epilepsy susceptible El mice was increased after seizure.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/11251211}, volume = {894}, year = {2001} }

TY - JOUR ID - citeulike:5916315 L3 - citeulike-article-id:5916315 N2 - It has been suggested that cyclooxygenase (COX)-2 and prostaglandin play a role in epilepsy. We studied the expression of COX-2 in the hippocampus and the effect of oral administration of indomethacin, a COX inhibitor, on seizure activity in genetically seizure-susceptible El mice. COX-2 protein significantly increased in the hippocampi of El mice after epileptic seizure. Indomethacin did shorten the duration from seizure onset to full recovery in El mice although the threshold and the duration of seizure were not changed. IS - 2 JF - Brain research SN - 0006-8993 EP - 335 TI - Cyclooxygenase-2 expression in the hippocampus of genetically epilepsy susceptible El mice was increased after seizure. VL - 894 SP - 332 KW - cyclooxygenase KW - cyclooxygenase-2 KW - el KW - epilepsy KW - hippocampus KW - mice KW - seizure KW - susceptible AU - Okada, K AU - Yuhi, T AU - Tsuji, S AU - Yamashita, U PY - 2001/03/16/ UR - http://view.ncbi.nlm.nih.gov/pubmed/11251211 ER -