MicroRNAs: small RNAs with a big role in gene regulation Export

@article{citeulike:1031386, abstract = {MicroRNAs are a family of small, non-coding RNAs that regulate gene expression in a sequence-specific manner. The two founding members of the microRNA family were originally identified in Caenorhabditis elegans as genes that were required for the timed regulation of developmental events. Since then, hundreds of microRNAs have been identified in almost all metazoan genomes, including worms, flies, plants and mammals. MicroRNAs have diverse expression patterns and might regulate various developmental and physiological processes. Their discovery adds a new dimension to our understanding of complex gene regulatory networks.}, address = {Cold Spring Harbor Laboratory, Watson School of Biological Sciences, 1 Bungtown Road, Cold Spring Harbor, New York 11724, USA.}, author = {He, Lin and Hannon, Gregory J.}, citeulike-article-id = {1031386}, citeulike-linkout-0 = {http://dx.doi.org/10.1038/nrg1379}, citeulike-linkout-1 = {http://dx.doi.org/10.1038/nrg1379}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/15211354}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=15211354}, day = {01}, doi = {10.1038/nrg1379}, issn = {1471-0056}, journal = {Nature Reviews Genetics}, keywords = {mirna}, month = {July}, number = {7}, pages = {522--531}, posted-at = {2009-11-01 22:37:34}, priority = {0}, publisher = {Nature Publishing Group}, title = {MicroRNAs: small RNAs with a big role in gene regulation}, url = {http://dx.doi.org/10.1038/nrg1379}, volume = {5}, year = {2004} }

TY - JOUR ID - citeulike:1031386 L3 - citeulike-article-id:1031386 N2 - MicroRNAs are a family of small, non-coding RNAs that regulate gene expression in a sequence-specific manner. The two founding members of the microRNA family were originally identified in Caenorhabditis elegans as genes that were required for the timed regulation of developmental events. Since then, hundreds of microRNAs have been identified in almost all metazoan genomes, including worms, flies, plants and mammals. MicroRNAs have diverse expression patterns and might regulate various developmental and physiological processes. Their discovery adds a new dimension to our understanding of complex gene regulatory networks. IS - 7 JF - Nature Reviews Genetics SN - 1471-0056 AD - Cold Spring Harbor Laboratory, Watson School of Biological Sciences, 1 Bungtown Road, Cold Spring Harbor, New York 11724, USA. EP - 531 TI - MicroRNAs: small RNAs with a big role in gene regulation PB - Nature Publishing Group VL - 5 SP - 522 KW - mirna AU - He, Lin AU - Hannon, Gregory PY - 2004/07/01/ UR - http://dx.doi.org/10.1038/nrg1379 ER -