The role of analytical sciences in medical systems biology. Export

@article{citeulike:137436, abstract = {Medical systems biology has generated widespread interest because of its bold conception and exciting potential, but the field is still in its infancy. Although there has been tremendous progress achieved recently in generating, integrating and analysing data in the medical and pharmaceutical field, many challenges remain, especially with respect to the crucial core technologies required for analytical characterization. This review briefly summarizes these aspects for metabolomics, proteomics, data handling and multivariate biostatistics.}, address = {TNO Systems Biology, PO Box 360, 3700 AJ Zeist, The Netherlands. vandergreef@pharma.tno.nl}, author = {van der Greef, J. and Stroobant, P. and van der Heijden, R.}, citeulike-article-id = {137436}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.cbpa.2004.08.013}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/15450501}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=15450501}, citeulike-linkout-3 = {http://www.sciencedirect.com/science/article/B6VRX-4D5PBH3-2/2/c604121faa82161a8fdd94a5f0bb67f6}, doi = {10.1016/j.cbpa.2004.08.013}, issn = {1367-5931}, journal = {Curr Opin Chem Biol}, keywords = {disease, expt-technique, metabolic, metabolic-review}, month = {October}, number = {5}, pages = {559--565}, posted-at = {2007-09-04 21:57:55}, priority = {2}, title = {The role of analytical sciences in medical systems biology.}, url = {http://dx.doi.org/10.1016/j.cbpa.2004.08.013}, volume = {8}, year = {2004} }

TY - JOUR ID - citeulike:137436 L3 - citeulike-article-id:137436 N2 - Medical systems biology has generated widespread interest because of its bold conception and exciting potential, but the field is still in its infancy. Although there has been tremendous progress achieved recently in generating, integrating and analysing data in the medical and pharmaceutical field, many challenges remain, especially with respect to the crucial core technologies required for analytical characterization. This review briefly summarizes these aspects for metabolomics, proteomics, data handling and multivariate biostatistics. IS - 5 JF - Curr Opin Chem Biol SN - 1367-5931 AD - TNO Systems Biology, PO Box 360, 3700 AJ Zeist, The Netherlands. vandergreef@pharma.tno.nl EP - 565 TI - The role of analytical sciences in medical systems biology. VL - 8 SP - 559 KW - disease KW - expt-technique KW - metabolic KW - metabolic-review AU - van der Greef, J AU - Stroobant, P AU - van der Heijden, R PY - 2004/10// UR - http://dx.doi.org/10.1016/j.cbpa.2004.08.013 ER -