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Anal. Chem. In Analytical Chemistry, Vol. 83, No. 1. (4 November 2010), pp. 2-7, doi:10.1021/ac101565f Key: citeulike:11218949
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Nanostructure-Initiator Mass Spectrometry (NIMS) is a matrix-free desorption/ionization approach that is particularly well-suited for unbiased (untargeted) metabolomics. An overview of the NIMS technology and its application in the detection of biofluid and tissue metabolites are presented. (To listen to a podcast about this feature, please go to the Analytical Chemistry multimedia page at pubs.acs.org/page/ancham/audio/index.html .)
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