Evidence that personality traits are related to health behaviours and health outcomes is emerging. This is interesting, but is it important? How can psychologists and healthcare professionals apply this knowledge? Can personality-health research offer anything practical that would improve health of the population? This article proposes a new typology, the Five T’s, which are potential ‘next steps’ for personality-health research: targeting, tailoring, training, treatment and transformation. It is pertinent to ask what the ultimate aims of establishing a causal link between personality and health might be, and how the Five T’s might be evaluated in future research. Getting psychologists ‘on board’ is an important part of that future.