Are childhood socio-economic circumstances related to coronary heart disease risk? Findings from a population-based study of older men Export

@article{citeulike:4900267, abstract = {Background The independent influence of childhood social circumstances on health in later life remains uncertain. We examined the extent to which childhood socio-economic circumstances are related to the risk of coronary heart disease (CHD) in older British men, taking account of adult social class and behavioural risk factors. Methods A socio-economically representative sample of 5552 British men (52-74 years) with retrospective assessment of childhood socio-economic circumstances (father's occupation and childhood household amenities) who were followed up for CHD (fatal and non-fatal) for 12 years. Results Men whose childhood social class was manual had an increased hazard ratio (HR) 1.34 (95\% CI 1.11-1.63)--this effect was diminished when adjusted for adult social class and adult behavioural risk factors (cigarette smoking, alcohol, physical activity and body weight) (HR 1.19; 95\% CI 0.97-1.46). Men whose family did not own a car in their childhood were at increased CHD risk even after adjustments for adult social class and behaviours (HR 1.35, 95\% CI 1.04-1.75). Men with combined exposure to both childhood and adult manual social class had the highest risk of CHD (HR 1.51; 95\% CI 1.19-1.91); this was substantially reduced by adjustment for adult behavioural risk factors (adjusted HR 1.28; 95\% CI 0.99-1.65). Conclusions Less affluent socio-economic conditions in childhood may have a modest persisting influence on risk of CHD in later life. 10.1093/ije/dym060}, author = {Ramsay, Sheena E. and Whincup, Peter H. and Morris, Richard W. and Lennon, Lucy T. and Wannamethee, S. G.}, citeulike-article-id = {4900267}, citeulike-linkout-0 = {http://dx.doi.org/10.1093/ije/dym060}, citeulike-linkout-1 = {http://ije.oxfordjournals.org/cgi/content/abstract/36/3/560}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/17440028}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=17440028}, doi = {10.1093/ije/dym060}, journal = {Int. J. Epidemiol.}, keywords = {lifecourse}, month = {June}, number = {3}, pages = {560--566}, posted-at = {2009-06-19 05:51:16}, priority = {2}, title = {Are childhood socio-economic circumstances related to coronary heart disease risk? Findings from a population-based study of older men}, url = {http://dx.doi.org/10.1093/ije/dym060}, volume = {36}, year = {2007} }

TY - JOUR ID - citeulike:4900267 L3 - citeulike-article-id:4900267 N2 - Background The independent influence of childhood social circumstances on health in later life remains uncertain. We examined the extent to which childhood socio-economic circumstances are related to the risk of coronary heart disease (CHD) in older British men, taking account of adult social class and behavioural risk factors. Methods A socio-economically representative sample of 5552 British men (52-74 years) with retrospective assessment of childhood socio-economic circumstances (father's occupation and childhood household amenities) who were followed up for CHD (fatal and non-fatal) for 12 years. Results Men whose childhood social class was manual had an increased hazard ratio (HR) 1.34 (95% CI 1.11-1.63)--this effect was diminished when adjusted for adult social class and adult behavioural risk factors (cigarette smoking, alcohol, physical activity and body weight) (HR 1.19; 95% CI 0.97-1.46). Men whose family did not own a car in their childhood were at increased CHD risk even after adjustments for adult social class and behaviours (HR 1.35, 95% CI 1.04-1.75). Men with combined exposure to both childhood and adult manual social class had the highest risk of CHD (HR 1.51; 95% CI 1.19-1.91); this was substantially reduced by adjustment for adult behavioural risk factors (adjusted HR 1.28; 95% CI 0.99-1.65). Conclusions Less affluent socio-economic conditions in childhood may have a modest persisting influence on risk of CHD in later life. 10.1093/ije/dym060 IS - 3 JF - Int. J. Epidemiol. EP - 566 TI - Are childhood socio-economic circumstances related to coronary heart disease risk? Findings from a population-based study of older men VL - 36 SP - 560 KW - lifecourse AU - Ramsay, Sheena AU - Whincup, Peter AU - Morris, Richard AU - Lennon, Lucy AU - Wannamethee, SG PY - 2007/06/01/ UR - http://dx.doi.org/10.1093/ije/dym060 ER -