Models of Molecular Evolution and Phylogeny Export

@article{citeulike:2864340, abstract = {10.1101/gr.8.12.1233 Phylogenetic reconstruction is a fast-growing field that is enriched by different statistical approaches and by findings and applications in a broad range of biological areas. Fundamental to these are the mathematical models used to describe the patterns of DNA base substitution and amino acid replacement. These may become some of the basic models for comparative genome research. We discuss these models, including the analysis of observed DNA base and amino acid mutation patterns, the concept of site heterogeneity, and the incorporation of structural biology data, all of which have become particularly important in recent years. We also describe the use of such models in phylogenetic reconstruction and statistical methods for the comparison of different models.}, address = {Department of Genetics, University of Cambridge, Cambridge CB2 3EH, UK.}, author = {Li\`{o}, P. and Goldman, N.}, citeulike-article-id = {2864340}, citeulike-linkout-0 = {http://dx.doi.org/10.1101/gr.8.12.1233}, citeulike-linkout-1 = {http://genome.cshlp.org/content/8/12/1233.abstract}, citeulike-linkout-2 = {http://genome.cshlp.org/content/8/12/1233.full.pdf}, citeulike-linkout-3 = {http://view.ncbi.nlm.nih.gov/pubmed/9872979}, citeulike-linkout-4 = {http://www.hubmed.org/display.cgi?uids=9872979}, citeulike-linkout-5 = {http://view.ncbi.nlm.nih.gov/pubmed/9872979}, day = {1}, doi = {10.1101/gr.8.12.1233}, issn = {1088-9051}, journal = {Genome Research}, keywords = {goldmanlab}, month = {December}, number = {12}, pages = {1233--1244}, posted-at = {2008-12-01 10:59:14}, priority = {2}, title = {Models of Molecular Evolution and Phylogeny}, url = {http://dx.doi.org/10.1101/gr.8.12.1233}, volume = {8}, year = {1998} }

TY - JOUR ID - citeulike:2864340 L3 - citeulike-article-id:2864340 N2 - 10.1101/gr.8.12.1233 Phylogenetic reconstruction is a fast-growing field that is enriched by different statistical approaches and by findings and applications in a broad range of biological areas. Fundamental to these are the mathematical models used to describe the patterns of DNA base substitution and amino acid replacement. These may become some of the basic models for comparative genome research. We discuss these models, including the analysis of observed DNA base and amino acid mutation patterns, the concept of site heterogeneity, and the incorporation of structural biology data, all of which have become particularly important in recent years. We also describe the use of such models in phylogenetic reconstruction and statistical methods for the comparison of different models. IS - 12 JF - Genome Research SN - 1088-9051 AD - Department of Genetics, University of Cambridge, Cambridge CB2 3EH, UK. EP - 1244 TI - Models of Molecular Evolution and Phylogeny VL - 8 SP - 1233 KW - goldmanlab AU - Liò, P AU - Goldman, N PY - 1998/December/01/ UR - http://dx.doi.org/10.1101/gr.8.12.1233 ER -